Latest Documents

OECD work on in vitro assays for developmental neurotoxicity

Discover OECD work on in vitro assays for developmental neurotoxicity

Section 4: Health Effects

Interested parties are invited to send their comments on the Draft Updated Performance Standards for in vitro reconstructed human cornea-like epithelium (RHCE) Test Methods for eye hazard identification by 28 February 2023.

Webinar Series on Emerging Science to Improve Chemical Safety

Emerging technologies of common interest will offer opportunities to develop, standardise and harmonise novel methods and approaches into Test Guidelines. This workshop aimed to identify where practice and process could evolve for the OECD Test Guidelines Programme to remain relevant and useful to support country chemicals regulations.

Draft Guidance and Review Documents/Monographs

Interested parties are invited to send their comments on the Draft Test Guideline: Determination of the Hydrophobicity Index of Nanomaterials Through an Affinity Measurement (Jan 2023) by 9 February 2023.

Webinar Series on Testing and Assessment Methodologies

7 February 2023 at 14:00-16:00 CET / 08:00-10:00 EST | This webinar will present the methods described in Test Guideline No. 125 to determine the size and size distributions of nanomaterial particles and fibres spanning from 1 nm to 1000 nm. During this webinar, you will be able to learn the use and limitation of this Test Guideline, as well as on the validation exercise that was done to support its development.

OECD Good Laboratory Practice: Frequently asked questions (FAQ)

GLP issues raised by testing labs are covered in this comprehensive list of questions and answers, recently updated with questions related to: Test Facility organisation and personnel, Quality Assurance, Equipment and computerized systems, Test items, reference items and samples/specimens (Biologicals, GMOs, etc.), SOPs, Management of the study, Histopathology, Archives and E-Archives and Monitoring Test Facility compliance by GLP CMAs.

Essai n° 442D: Sensibilisation cutanée in vitro - Méthode d'essai ARE-Nrf2 luciférase

Ongoing Peer Reviews

Peer review package of the Test Guideline 442C Amino acid Derivative Reactivity Assay (ADRA)

OECD Work Related to Bees/Pollinators

There have been reports these last years of declines in native and managed pollinators in several regions of the world. Potential factors associated with these declines are hypothesised to include habitat destruction, predators, certain agricultural practices, bee management practices, pathogens, climate change, nutrition and pesticides. There is uncertainty regarding the extent to which pesticides contribute to pollinator declines.

Essai n° 405 : Effet irritant/corrosif aigu sur les yeux