A common urban mobility plan for Prague and its metropolitan region as well as the creation of an integrated transport system coordinated by a central transport body are the main assets Prague can leverage to enhance accessibility. However, weak links to land use plans, the lack of enforceability of the mobility strategy, the absence of a transport component in the urban renewal strategy, and the high level of administrative fragmentation of the metro area limit the impact of the transport network in facilitating access to jobs and services. This paper aims at drawing policy lessons from Prague’s mobility strategy and suggesting recommendations that could improve its effectiveness in enhancing accessibility.