Latest Documents

Series on Testing and Assessment: publications by number

The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). The objective is to increase experience with the use of IATA by developing case studies, which constitute examples of predictions that are fit for regulatory use.

OECD work on in vitro assays for developmental neurotoxicity

Discover OECD work on in vitro assays for developmental neurotoxicity

Section 4: Health Effects

Interested parties are invited to send their comments on the Draft Updated Performance Standards for in vitro reconstructed human cornea-like epithelium (RHCE) Test Methods for eye hazard identification by 28 February 2023.

Webinar Series on Emerging Science to Improve Chemical Safety

Emerging technologies of common interest will offer opportunities to develop, standardise and harmonise novel methods and approaches into Test Guidelines. This workshop aimed to identify where practice and process could evolve for the OECD Test Guidelines Programme to remain relevant and useful to support country chemicals regulations.

Draft Guidance and Review Documents/Monographs

Interested parties are invited to send their comments on the Draft Test Guideline: Determination of the Hydrophobicity Index of Nanomaterials Through an Affinity Measurement (Jan 2023) by 9 February 2023.

Webinar Series on Testing and Assessment Methodologies

7 February 2023 at 14:00-16:00 CET / 08:00-10:00 EST | This webinar will present the methods described in Test Guideline No. 125 to determine the size and size distributions of nanomaterial particles and fibres spanning from 1 nm to 1000 nm. During this webinar, you will be able to learn the use and limitation of this Test Guideline, as well as on the validation exercise that was done to support its development.

Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

This new release includes four single AOPs and a network of five AOPs addressing various toxicological and ecotoxicological pathways.

OECD Good Laboratory Practice: Frequently asked questions (FAQ)

GLP issues raised by testing labs are covered in this comprehensive list of questions and answers, recently updated with questions related to: Test Facility organisation and personnel, Quality Assurance, Equipment and computerized systems, Test items, reference items and samples/specimens (Biologicals, GMOs, etc.), SOPs, Management of the study, Histopathology, Archives and E-Archives and Monitoring Test Facility compliance by GLP CMAs.

Test No. 442D: In Vitro Skin Sensitisation - ARE-Nrf2 Luciferase Test Method

Good Laboratory Practice (GLP)

Read the countries' response to address the challenges posed by COVID-19 to GLP test facilities.