Latest Documents

Section 4: Health Effects

Interested parties are invited to send their comments on the following Draft Test Guideline No. 442C on In Chemico Skin Sensitisation: Draft updated Appendix I: Direct Peptide Reactivity Assay (DPRA). Comments should be sent by 20 June 2022.

Draft Guidance and Review Documents/Monographs

Interested parties are invited to send their comments on the Draft Guidance on Evaluation of Data from the Developmental Neurotoxicity (DNT) In-Vitro Testing Battery on 15 June 2022.

Webinar Series on Testing and Assessment Methodologies

On 6 April 2022, the OECD organised a second webinar on the application of the assessment framework for Physiologically Based Kinetic (PBK) models. The webinar presented two case studies and illustrated how the templates of the guidance were used to report and evaluate PBK models. A discussion took place on challenges related to the regulatory evaluation of PBK models and clarifications on aims and scope of these models were provided.

Webinar Series on Emerging Science to Improve Chemical Safety

On 16 March, the OECD and the EU Joint Research Centre organised a webinar to discuss the report on Addressing evidence needs in chemicals policy and regulation. It presented the main findings of the report and a set of actionable recommendations, including how knowledge management systems can be designed in a user-centric fashion to address current challenges, with the Adverse Outcome Pathway framework being a prominent example.

Good Laboratory Practice (GLP)

Read the countries' response to address the challenges posed by COVID-19 to GLP test facilities.

Ongoing Peer Reviews

Peer review package of the Test Guideline 442C Amino acid Derivative Reactivity Assay (ADRA)

Series on Testing and Assessment: publications by number

This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).

OECD Series on Principles of Good Laboratory Practice (GLP) and Compliance Monitoring

This OECD Advisory Document on Good Laboratory Practice (GLP) Data Integrity provides guidance for test facilities or test sites that conduct GLP studies and aims to promote a risk-based approach to the management of data.

OECD Work Related to Bees/Pollinators

There have been reports these last years of declines in native and managed pollinators in several regions of the world. Potential factors associated with these declines are hypothesised to include habitat destruction, predators, certain agricultural practices, bee management practices, pathogens, climate change, nutrition and pesticides. There is uncertainty regarding the extent to which pesticides contribute to pollinator declines.

Test No. 405: Acute Eye Irritation/Corrosion