Latest Documents

Draft Guidance and Review Documents/Monographs

Interested parties are invited to send their comments on the Draft revised Guidance Document no 75 on the Honey Bee (Apis mellifera L.) Brood Test under Semi-Field Conditions by 24 January 2024.

Webinar Series on Testing and Assessment Methodologies

Two webinars were held by the OECD, which aimed to provide training and orientation on method validation at the OECD, and to help researchers become familiar with method readiness evaluation.

Section 4: Health Effects

Interested parties are invited to send their comments on the Draft Updated TG 467 Part III: Defined Approach on Eye Irritation for Solids by 22 December 2023.

Adverse Outcome Pathways

The OECD released four new Adverse Outcome Pathways following scientific review and OECD endorsement.

Series on Testing and Assessment: publications by number

The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). The objective is to increase experience with the use of IATA by developing case studies, which constitute examples of predictions that are fit for regulatory use.

OECD work on Chemical Safety and Biosafety brochure 2021-24

This new edition of the OECD work on Chemical Safety and Biosafety highlights the activities, results and ongoing projects as outlined by the 2021-2024 work programme.

OECD Work Related to Bees/Pollinators

There have been reports these last years of declines in native and managed pollinators in several regions of the world. Potential factors associated with these declines are hypothesised to include habitat destruction, predators, certain agricultural practices, bee management practices, pathogens, climate change, nutrition and pesticides. There is uncertainty regarding the extent to which pesticides contribute to pollinator declines.

Good Laboratory Practice (GLP)

The OECD Principles of Good Laboratory Practice (GLP) ensure the generation of high quality and reliable test data related to the safety of industrial chemical substances and preparations. The principles have been created in the context of harmonising testing procedures for the Mutual Acceptance of Data (MAD).

Ongoing Peer Reviews

Peer review package of the Test Guideline 442C Amino acid Derivative Reactivity Assay (ADRA)

Test No. 487: In Vitro Mammalian Cell Micronucleus Test