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Testing of chemicals

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  • Webinar: Register to join our talk on the Adverse Outcome Pathway framework

    Join us on 30 April 2019 to learn and discuss the Adverse Outcome Pathway (AOP) framework. The AOP framework is a collaborative tool that applies an innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.

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  • Report: Saving Costs in Chemicals Management - How the OECD Ensures Benefits to Society

    The Saving Costs in Chemicals Management report estimates that the OECD Environment Health and Safety Programme saves governments and industry around EUR 309 million a year. Find out how governments are working together to tackle the risks posed by chemicals.

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  • Three new publications on Adverse Outcome Pathways

    The first publication describes the linkage between inhibition of complex I of the mitochondrial respiratory chain and motor deficit as in parkinsonian disorders. The second publication links chronic binding of antagonist to N-methyl-D-aspartate receptors during brain development leading to neurodegeneration. The third publication details the linkage between binding and activation of androgen receptor leading to reproductive dysfunction.

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OECD assists countries in harmonising Guidelines for the Testing of Chemicals and Good Laboratory Practice, in order to ensure high quality and reliable data and for countries and industry to fully benefit from the OECD agreement on Mutual Acceptance of Data (MAD) and avoid duplicative testing.

 

Saving costs in Chemicals Management with the Mutual Acceptance of Data system

 

Did you know?

By reducing duplication, and creating a framework for the sharing of work, the Mutuall Acceptance of Data system saves governments and industry around € 309 million each year, as well as reduces the number of animals used in such testing. 

Source: Saving Costs in Chemicals Management, OECD (2019).

Key areas of work

> OECD Guidelines for the Testing of Chemicals 

> Good Laboratory Practice

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PUBLICATIONS

Saving Costs in Chemicals Management


 Saving costs in chemicals management cover

 

Guidance Document on evaluating Chemicals for Endocrine Disruption


 This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.

 

Guidance Document on Good In Vitro Method Practices (GIVIMP)

 

 Guidance Document on Good In Vitro Methods Practices (GIVIMP)

 

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