In order to provide experts with a forum to present and discuss developments in the field of partitioning and transmutation (P&T), the OECD Nuclear Energy Agency (NEA) has been organising, since 1990, a series of biennial information exchange meetings on actinide and fission product P&T. These proceedings contain all the technical papers presented at the 11th Information Exchange Meeting, which was held on 1-4 November 2010 in San Francisco, California, USA. The meeting covered national programmes on P&T; fuel cycle strategies and transition scenarios; waste forms and geological disposal; transmutation fuels and targets; pyro and aqueous processes; transmutation physics and materials; and transmutation system design, performance and safety.