This Test Guideline addresses the human health endpoint skin corrosion. It is based on the rat skin transcutaneous electrical resistance (TER) test method, which utilizes skin discs to identify corrosives by their ability to produce a loss of normal stratum corneum integrity and barrier function. This Test Guideline was originally adopted in 2004 and updated in 2015 to refer to the IATA guidance document.
Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER)
OECD Guidelines for the Testing of Chemicals, Section 4
