Performance Standards for the Assessment of Proposed Similar or Modified In Vitro Epidermal Sensitisation Assay (EpiSensA) Test Methods

This document contains the Performance Standards (PS) for the assessment of proposed in vitro assays, similar to the in vitro Epidermal Sensitisation Assay (EpiSensA), or modified. The EpiSensA is an in vitro method for identifying the skin sensitisation potential of chemicals. The EpiSensA method has been included in Test Guideline 442D, upon a proposal from Japan, reviewed, consolidated and finally approved by the Working Party of the National Coordinators of the Test Guidelines Programme. This was a project on the work plan of the Test Guidelines Programme until 2024.