This Best Practice Guide (BPG) was developed to support the implementation of the OECD Recommendation of the Council Concerning Access and Protection of Proprietary Rights to Non-Clinical Health, Safety and Environmental Data and Information on Chemicals. This Recommendation aims to protect both the public and the data owners by keeping a balance between the access of the public to chemical safety data and the protection of the proprietary rights associated with these results. This BPG provides a collection of existing good approaches by governments and industry for disclosing health, safety and environmental data while protecting their proprietary rights.