The OECD has just published two new Test Guidelines on human health hazard endpoint skin sensitisation. Skin sensitisation refers to an allergic response following skin contact with the tested chemical, as defined by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS).
This toolbox is a compilation of resources relevant to chemical substitution and alternatives assessments. Alternative assessments are processes for identifying, comparing and selecting safer alternatives to replace hazardous chemicals with the objective of promoting sustainable production and consumption.
Micro-organisms play a fundamental role in the environment. Yet their role is the result of complex biogeochemical processes by consortia of micro-organisms and the function of individual species is not clear in many cases. This publication provides an overview of the current situation and relevant developments in environmental microbiology.
Micro-organisms play a fundamental role in the environment. Yet their role is the result of complex biogeochemical processes by consortia of micro-organisms and the function of individual species is not clear in many cases.
This publication provides an overview of the current situation and relevant developments in environmental microbiology, as well as its potential application, which covers: use of micro-organisms for agriculture, production purposes, bioremediation, and cleaning purpose; environmental applications of microbial symbionts of insects; and environmental risk/safety assessment of the deliberate release of engineered micro-organisms.
An addendum to the OECD Guiding Principles on Chemical Accident Prevention, Preparedness and Response to address Natural Hazards Triggering Technological Accidents (Natech) Risk Management has just been published. The addendum consists of a number of amendments to the Guiding Principles and the addition of a new Chapter to provide more detailed guidance on Natech prevention, preparedness and response.
This page explains the background to the OECD Test Guidelines, the reason for their development, their applicability and how they can be accessed.
The objective of these Guiding Principles is to set out general guidance for the safe planning, construction, management, operation and review of safety performance of hazardous installation in order to prevent accidents involving hazardous substances and, recognising that such accidents may nonetheless occur, to mitigate adverse effects through effective land-use planning and emergency preparedness and response.
This guidance is intended to harmonise the way non-guideline in vitro test methods are described. This should in future facilitate an assessment of the relevance of test methods for biological activities and responses of interest, of the quality of data produced, irrespective of whether these tests are based on manual protocols or assay protocols adapted for use on automated platforms or high-throughput screening systems (HTS).
Children can be more vulnerable than adults to chemicals. Considering global concern for children’s health, the OECD has been working to bring together knowledge and experiences to reduce risks to children’s health from chemicals.
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