This work describes the various endeavours of OECD countries to develop harmonised methodologies for birds toxicity testing, including the successful outcomes or the reasons for stopping activities in some cases. The work has required commitment from countries and industry in terms of staffing and laboratory resources to perform experimental testing and generate data.
Draft Guidance Documents: draft Validation of the (anti-) ERα CALUX bioassay; and Study for Androgen Receptor (AR)-mediated stably transfected transcriptional activation (AR-STTA), deadline for public comment set for 5 February 2016.
New deadlines for comments: Test Guidelines (TG) 402 on Acute Dermal Toxicity and scoping document; Draft updated TG 412 on 28-d repeated dose inhalation toxicity study; Draft updated TG 413 on 90-d repeated dose inhalation; Draft revised TG 438 on Isolated Chicken eye test document toxicity study and Supporting document for amending Decision Criteria in TG 438.
This is a list of the Guidelines for the Testing of Chemicals in Section 2: Effects on Biotic Systems
English, PDF, 771kb
This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test.
English, PDF, 184kb
This Test Guideline is designed for assessing the effects of chemicals on the reproductive output of the collembolans in soil. It is based on existing procedures (1) (2). The parthenogenetic Folsomia candida and sexually reproducing Folsomia fimetaria are two of the most accessible species of Collembola, and they are culturable and commercially available.
In 2011, Brazil joined OECD’s Mutual Acceptance of Data (MAD) system ensuring that its chemical safety test data will be accepted by all 40 countries adhering to MAD. Originally limited to data developed in Brazil on pesticides, biocides and industrial chemicals, it now also includes veterinary products, feed additives, cosmetics, pharmaceutical products, sanitizers, wood preservative and treatments of effluents and natural ecosystems.
The OECD has just published two new Test Guidelines on human health hazard endpoint skin sensitisation. Skin sensitisation refers to an allergic response following skin contact with the tested chemical, as defined by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS).
This page explains the background to the OECD Test Guidelines, the reason for their development, their applicability and how they can be accessed.