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  • 6-December-2018

    English

    Considerations for Assessing the Risks of Combined Exposure to Multiple Chemicals

    The report outlines the technical aspects of the various approaches and methodologies available with respect to the assessment of risks from combined exposures to multiple chemicals. The document draws from approaches applied and experience gained in the regulatory context and will therefore be most relevant to the regulatory authorities addressing chemicals, the regulated community and other interested stakeholders. The considerations are not presented as strict guidance but rather elements to recognise in assessing combined exposures to multiple chemicals.
  • 21-November-2018

    English

    Working Document on the Risk Assessment of Secondary Metabolites of Microbial Biocontrol Agents

    This working document has been prepared to address the assessment of secondary metabolites of microbial biocontrol agents. The main focus of this working document is the assessment of the hazards and risk of secondary metabolites produced during the manufacturing of microbial pest control products and after their application in the field. This document addresses a number of important topics for secondary metabolites, including concerns that microbial pest control products could be associated with known or as yet uncharacterised ‘new’ secondary metabolites. A background document is available as an annex to help provide clarity on issues and terminology related to secondary metabolites of microbial biocontrol agents. This document may also form the basis of a future OECD Guidance Document on the subject.
  • 19-November-2018

    English

    OECD Product Release and Exposure Data Warehouse

    The Product Release and Exposure Data Warehouse is a Microsoft® Access 2016 database is designed to house existing data on releases of chemicals from, and exposures to, commercial and consumer end products. A number of forms provide a simple approach to data entry and access to the existing data.

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  • 2-November-2018

    English

    Missed our latest webinar: Toward greener water and oil repellents in the textile industry? Watch the video recording

    On 30 October 2018, Eeva Leinala of the OECD Environment Directorate; Ruth Garcia, Gemma Janer and Marc Torrentellé from LEITAT; and Julio Fierro of the Centro Tecnológico de Investigación Multisectorial presented the MIDWOR-LIFE project that aims to mitigate the environmental, health and safety impacts of current Durable Water & Oil Repellents and available alternatives by looking at their environmental impact & technical performance.

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  • 30-October-2018

    English

    Join our Webinar on Tuesday 30 October @ 1 pm: Toward greener water and oil repellents in the textile industry - case study

    The webinar will present the MIDWOR-LIFE project that aims to mitigate the environmental, health and safety impacts of current Durable Water and Oil Repellents and available alternatives by looking at their environmental impact and technical performance.

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  • 22-October-2018

    English

    Assessing the economic valuation of the benefits of regulating chemicals - Environment Working Paper

    This paper reviews and compares five case studies on quantification and economic valuation of benefits in cost-benefit analyses (CBAs) of regulating phthalates, mercury, PFOA (perfluoro-octanic acid) and its salts, NMP (1 methyl-2-pyrroloidine) and formaldehyde. The case studies had all been carried out as part of the SACAME project, and the purpose of the present paper is to draw out cross-cutting findings from these studies.

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  • 12-September-2018

    English

    Webinar: Best Environmental Practices (BEP) for textiles in the context of management of per- and polyfluoroalkyl Substances (PFASs)

    Join us for our per- and polyfluoroalkyl substances webinar on Best Environmental Practices (BEP) for Textiles

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  • 4-September-2018

    English

    Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption

    This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals. The document is intended to provide guidance for evaluating chemical using standardised test guidelines.

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  • 4-September-2018

    English

    Guidance Document on Good In Vitro Method Practices (GIVIMP)

    GIVIMP aims to reduce the uncertainties in cell and tissue-based in vitro method derived predictions by applying good scientific, technical and quality practices from method development to implementation for regulatory use. Test method developers and test guideline users will find best practices for designing guideline in vitro methods, carrying out safety tests and assuring quality and scientific integrity of the resulting data

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  • 3-September-2018

    English

    Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption

    This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals. The document is intended to provide guidance for evaluating chemical using standardised test guidelines. Specific objectives include providing a description of the OECD conceptual framework for evaluating chemicals for endocrine disruption, background on the standardised test methods used, and guidance for interpreting the outcome of individual tests. The general approach taken by the document is primarily to provide guidance on how test results might be interpreted based on the outcome of standardised assays. Key questions addressed in the document concern likely mechanisms of endocrine action and any resulting apical effects that can be attributed to such action. The document is not proscriptive but provides suggestions for possible next steps in testing (if any) which might be appropriate for a regulatory authority to take, given the various data scenarios. The guidance document is focused primarily on endocrine modalities included in the conceptual framework; estrogen, androgen, and thyroid mediated endocrine disruption and chemicals that interfer with steroidogenesis.
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