The OECD webinars on Testing and Assessment Methodologies focus on selected ongoing projects that will result in the short to medium term in new methodologies to test and assess chemicals. These free webinars are open to potential end users among regulators and contract research organisations who want to get familiar with new standards and approaches. Video recordings of our webinars are made available online afterwards.
WEBINAR on the Implementation of the first stand-alone NAMs for eye hazard identification into OECD Guidelines: OECD GL 467 and TG 492B
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WHEN: Tuesday 27 September 2022 at 14:00 - 15:30 (CEST) / 08:00 - 09:30 (EDT) In the past decade, a number of Non-Animal Methods (NAMs) for predicting eye hazards of chemicals have been adopted as OECD Test Guidelines. However, to this date, no single NAM could completely replace the in vivo Draize eye test method due to the difficulty with predicting the middle category (i.e., eye irritation) for eye hazards. Studies have shown that this difficulty is linked to the eye irritation being caused by multiple drivers as well as the variability and inconsistency within the results from the Draize eye test, which is used as reference data for evaluating the predictive capacity of the NAMs for eye hazard identification. The newly adopted OECD GL 467 on Defined Approaches addresses this challenge and is the first stand-alone NAM based OECD Guideline. Defined approaches in OECD GL 467 use multiple information sources according to a fixed Data Interpretation Procedure (DIP) and allow for prediction of all eye hazard categories. The OECD also recently adopted TG 492B, another stand-alone NAM based OECD Guideline.
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The OECD is organising this webinar to increase the awareness of these newly adopted guidelines for regulatory acceptance and to recognise the efforts of the organisation, as well as its stakeholders to commit to 3R principles for chemical hazard testing.
This webinar will consist of three parts:
1) Draize eye test Reference Database (DRD)
2) OECD Guideline 467 on Defined Approaches for Serious Eye Damage and Eye Irritation
3) OECD Test Guideline 492B on Reconstructed Human Cornea-like Epithelium (RHCE) Test Method for Eye Hazard Identification.
MISSED OUR previous WEBINARS? WATCH THE VIDEO RECORDINGS
Webinar on Physiologically Based Kinetic (PBK) Models
6 April 2022: Gaining acceptance in next generation PBK modelling approaches for regulatory assessments: case studies | Access the presentations here.
10 May 2021: Gaining acceptance in next generation PBK modelling approaches for regulatory assessment | Access the presentation here.
Webinars on Adverse Outcome Pathways (AOPs)
25 January 2022: AOP co-operative activities between scientific journals and the OECD
30 November 2020: Training needs, resources, and opportunities for Adverse Outcome Pathways (AOPs) | Presentations:
30 January 2020: AOP knowledge base and AOP developing tips | Presentations:
15 January 2020: Assembling and evaluating weight of evidence and quantitative understanding | Presentations
30 April 2019: Adverse Outcome Pathway (AOP) framework | Presentations:
Webinars on Testing and Assessment Methodologies:
18 October 2021: Implementation of the Defined Approaches on Skin Sensitisation for Chemical Safety
Access the Question and Answers document here.
27 September 2019: OECD Alternatives to in vivo eye irritation testing
16 January 2019: Defined Approaches for Skin Sensitisation
Webinars on Nanomaterials:
2 December 2021: How to assess exposure to nanomaterials? The evaluation results of existing tools/models (English - Spanish)
The recording is available in Spanish / El video está disponible en español.
The recording is available in Spanish / El video está disponible en español.
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