OECD Expert Group on BioPesticides Seminar on Bioinformatics and Regulation of Microbial Pesticides

OECD Pesticides Expert Group on BioPesticides Seminar on “Bioinformatics and Regulation of Microbial Pesticides”

24 June 2019 OECD, Paris

The OECD Expert Group on BioPesticides Seminar on Bioinformatics and Regulation of Microbial Pesticides was organised to present and discuss the potential use of genome sequence, bioinformatic tools and databases in a regulatory decision process for microbials, as well as to initiate a dialogue on how this new technology can enrich the toolbox of evaluators for microbials.

Programme

Opening:

Welcome and opening remarks - Jeroen Meeussen, Chair of the OECD Expert Group on BioPesticides

Session 1

Introduction

Michel-Yves Mistou - Agency for Food, Environmental and Occupational Health and Safety (ANSES), France
Overview of the commonly used sequencing platforms, bioinformatic search tools and databases
Alexander Goesmann - University of Giessen, Germany
Bioinformatics and sequencing tools used in research and development
J.T. Wennmann and J.A. Jehle - Julius Kühn-Institut, Germany
Use of Next Generation Sequencing techniques for characterisation of baculoviruses

Session 2

Stakeholders' Experience and Perspectives

Scott McClain - Syngenta Crop Protection, presented by Greg Watson - Bayer Crop Science
Bioinformatics: Building the cornerstones of Sequence Homology and its use for Biologics [Strengths and weaknesses of bioinformatics and sequencing tools (within the context of how these tools might inform the regulatory process)]
Andre Silvanovich - Bayer Crop Science
How bioinformatic and sequencing data might inform the regulatory process
Rüdiger Hauschild - Applied Insect Science (APIS), Germany
How can Whole Genome Sequencing information be used to address data requirements for approval of microorganisms as active ingredients in plant protection products in the EU?

Session 3

Government Experience and Perspectives

Jürgen Sturma and Beatriz Guerra - European Food Safety Agency (EFSA), Italy
Potential value of bioinformatic analysis in regulatory process
Shannon Borges - Environmental Protection Agency (EPA), United States
US Perspective on use of bioinformatics in microbial pesticide regulation
Thierry Heger - Changins, The University of Applied Sciences Western Switzerland
High-throughput sequencing data of microorganisms opens new perspectives for ecotoxicological assessment of biopesticides in soils
Laurent Guillier - Agency for Food, Environmental and Occupational Health and Safety (ANSES), France
The use of Whole Genome Sequencing in risk assessment: Application to the cold smoked salmon-related listeriosis risk model
Simon Tausch - Federal Institute for Risk Assessment (BfR), Germany
Activities in development of bioinformatics pipelines for characterisation of foodborne pathogens

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