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Chemical safety and biosafety

OECD Test Guidelines for the Chemicals

 

 

Joint NanoHarmony and NANOMET-OECD webinar on the pathway to Test Guidelines: from science to standards for nanomaterials

On 16 November 2020, the NanoHarmony and NANOMET-OECD organised a webinar on the topic 'The pathway to Test Guidelines - from science to standards for nanomaterials'.  Find out how Test Guidelines are developed through the OECD, with case studies from the Test Guidelines being supported through the projects for expansion into nanomaterials. The webinar explained how novel methodologies are developed and approved through expert committees, eventually becoming internationally accepted standard methods used by governments, industry and independent laboratories to assess the safety of chemicals.

 

What's new

On 26 June, OECD adopted a set of updated and corrected Test Guidelines for chemicals safety testing to keep pace with scientific progress for OECD members and Mutual Acceptance of Data (MAD) adhering countries.

Eight Test Guidelines have been updated (TG 437, TG 458, TG 488, TG 491) and corrected (TG 405, TG 439, TG 442C et TG 471):

 

OECD Test Guidelines 

The OECD Guidelines for the Testing of Chemicals are a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as standard methods for safety testing, the Guidelines are used by professionals in industry, academia and government involved in the testing and assessment of chemicals (industrial chemicals, pesticides, personal care products, etc.). These Guidelines are continuously expanded and updated to ensure they reflect the state-of-the-art science and techniques to meet member countries regulatory needs. The Guidelines are elaborated with the assistance of experts from regulatory agencies, academia, industry, environmental and animal welfare organisations. 

OECD Test Guidelines are covered by the OECD Mutual Acceptance of Data (MAD) system. Under this system, laboratory test results related to the safety of chemicals that are generated in accordance with OECD Test Guidelines and OECD Principles of Good Laboratory Practices are accepted in all OECD countries and adherent countries for the purpose of safety assessment and other uses relating to the protection of human health and the environment.

 

The OECD Guidelines for the Testing of Chemicals are split into five sections:


The full list of adopted Test Guidelines, the draft TGs under public commenting rounds, the draft Guidance and review documents are available on the Test Guidelines Programme

 

Publications in the Series of Testing and Assessment

This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).

Find out more about our work 

Find out about our areas of work, upcoming webinars, programme of work and the Council Acts related to Test Guidelines. 

 

Test Guidelines that have been deleted or replaced by updated versions

The Test Guidelines that have been deleted should not be used for new testing. They are included here because it may be useful to consult them in the framework of the assessment of substances based on old study reports. The guaranties of Mutual Acceptance of Data (MAD) would not apply if these Test Guidelines were used for new testing.

In November 2012, the Joint Meeting of the Chemicals Committee and Working Party on Chemicals, Pesticides and Biotechnology decided on a transition period of 18 months, between the Council Decision and the effective deletion, for Test Guidelines that have been updated or deleted. For more information, please read the presentation: Update of Test Guidelines and the Mutual Acceptance of Data.

 

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