Assessment of Chemicals

Member countries and other stakeholders assess the hazards of industrial chemicals.

OECD facilitates the use of Quantitative Structure-Activity Relationships Project [(Q)SARs] for chemical assessment.

Tools are created for estimating the exposure of chemicals to humans and the environment through their production, use and disposal.

The tools developed for environmental risk assessment are accessible via the Environmental Risk Assessment Toolkit.

OECD harmonises activities concerning new chemicals to reduce work for governments and costs for industry.

What's new

The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins

15-May-2012

An adverse outcome pathway (AOP) is the sequence of events from the structure of a target chemical through the molecular initiating event to an in vivo adverse outcome. This document describes the state of knowledge of the AOP for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events and databases containing test results related to those key events [Part I]. AOPs can be incorporated into chemical categories-based assessments or integrated approaches for testing and assessment [Part II].

SPIN - Substances in Preparations In the Nordic countries Database has been added to eChemPortal

10-May-2012

The SPIN database contains information on chemical substances from the Nordic product registers (Denmark, Finland, Norway and Sweden). The types of information are: exposure assessments, use patterns, industrial chemicals and volumes. The Nordic SPIN database includes an Exposure Toolbox. The Use Index enables to search for general indicative exposure of human beings and the environment from different chemicals and uses. With the SPIN database, over 25000 records have been added in eChemPortal.

Two REACH submissions are the basis for OECD Hazard Assessments

19-Mar-2012

Dichloromethane (CAS. 75-09-2) and Carbon tetrachloride (CAS.56-23-5) were registered under REACH. The registrants, in collaboration with Switzerland, have reused the work done for REACH to submit a hazard assessment to the OECD Cooperative Chemicals Assessment Programme to reach international agreement. The conclusions are now publicly available from the Existing Chemicals database  and eChemPortal. Learn more about the OECD hazard assessment activities.

Modified OECD Environmental Risk Assessment Toolkit

19-Mar-2012

The OECD Environmental Risk Assessment Toolkit describes the work flow for environmental risk assessment and management of chemicals with links to available OECD material relevant for the different steps in risk assessment and management.  The Toolkit has been revised 1) to include resources other than OECD products, and 2) to incorporate three examples (i.e. textile dye, pesticide and environmental quality standard setting) which show the risk assessment steps involved in each case.

New Emission Scenario Document on Chemicals Used in Oil Well Production

19-Mar-2012

This OECD Emission Scenario Document (ESD) is intended to provide information on the sources, use patterns and release pathways of chemicals used in oil well production to assist in the estimation of releases of chemicals to the environment.

Update of QSAR Toolbox (version 2.3) now available for free download

13-Mar-2012

(Quantitative) Structure-Activity Relationships or (Q)SARs are methods for estimating properties of a chemical from its molecular structure. The QSAR Toolbox is a software intended to be used by governments, the chemical industry and other stakeholders to apply (Q)SARs to fill data gaps needed for assessing the hazards of chemicals. This updated version 2.3 contains a number of new functionalities, new databases and bug fixes. The release is part of a collaboration between OECD and the European Chemicals Agency.

Publication of OECD Hazard conclusions for chemicals investigated in the Cooperative Chemicals Assessment Programme

28-Feb-2012

The SIDS Initial Assessment Profiles (SIAPs) and Initial Targeted Assessment Profiles (ITAPs) for chemicals and categories assessed in the course of the OECD HPV Chemicals Assessment Programme from 1993 to 2011 have been collated in a publication in the OECD Series on Testing and Assessment. The document is divided in 6 chronological parts. This collection will facilitate retrieval of assessment profiles more broadly from the Internet.  The publication is the Monograph No 166 in the Series on Testing and Assessment.

Two additional databases : Combined Exposure and Australian NICNAS Other available on eChemPortal

03-Jan-2012

The Collection of Case Studies on Risk Assessments of Combined Exposures to Multiple Chemicals (Combined Exposures) can now be searched on eChemPortal. To date, it gathers 5 case studies from the WHO OECD ILSI/HESI International Workshop on Risk Assessment of Combined Exposures to Multiple Chemicals.
The Australian NICNAS Other database contains Hazard assessment reports on existing chemicals other than Priority Existing Chemical assessments.

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