Publications


  • 28-July-2015

    English

    Test No. 241: The Larval Amphibian Growth and Development Assay (LAGDA)

    The test guideline of the Larval Amphibian Growth and Development Assay (LAGDA) describes a toxicity test with an amphibian species (African clawed frog (Xenopus laevis)) that considers growth and development from fertilization through the early juvenile period.  It is an assay (typically 16 weeks) that assesses early development, metamorphosis, survival, growth, and partial reproductive maturation. It also enables measurement of a suite of other endpoints that allows for diagnostic evaluation of suspected endocrine disrupting chemicals (EDCs) or other types of developmental and reproductive toxicants. The LAGDA serves as a higher tier test with an amphibian for collecting more comprehensive concentration-response information on adverse effects suitable for use in hazard identification and characterization, and in ecological risk assessment. The general experimental design entails exposing X. laevis embryos at Nieuwkoop and Faber (NF) stage 8-10 (3) to a minimum of four different concentrations of test chemical and control(s) until 10 weeks after the median time to NF stage 62.  There are four replicates in each test concentration with eight replicates for the control. Endpoints evaluated during the course of the exposure (at the interim sub-sample and final sample at completion of the test) include those indicative of generalized toxicity: mortality, abnormal behaviour, and growth determinations (length and weight), as well as endpoints designed to characterize specific endocrine toxicity modes of action targeting oestrogen, androgen or thyroid-mediated physiological processes.

  • 28-July-2015

    English

    Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test

    This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance. It has been updated with endocrine disruptor endpoints, in particular measure of anogenital distance and male nipple retention in pups and thyroid examination.

    The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 63 days. Matings "one male to one female" should normally be used in this study. This Test Guideline is designed for use with the rat. It is recommended that each group be started with at least 10 animals of each sex. Generally, at least three test groups and a control group should be used. Dose levels may be based on information from acute toxicity tests or on results from repeated dose studies. The test substance is administered orally and daily. The results of this study include clinical observations, body weight and food/water consumption, oestrous cycle monitoring, offspring parameters observation/measurement, thyroid hormone measurement, as well as gross necropsy and histopathology. The findings of this toxicity study should be evaluated in terms of the observed effects, necropsy and microscopic findings. Because of the short period of treatment of the male, the histopathology of the testis and epididymus should be considered along with the fertility data, when assessing male reproductive effects.

  • 27-July-2015

    English

    Towards Green Growth? - Tracking Progress

    The 2011 Green Growth Strategy provided initial guidance to governments on how to achieve economic growth and development, while preventing costly environmental damage and inefficient resource use. What progress have countries made in aligning economic and environmental priorities since 2011? This report attempts to evaluate this progress and highlight where there is broad scope to heighten the ambition and effectiveness of green growth policy. It draws lessons from green growth mainstreaming across the OECD’s work programme, notably in terms of how governments can maximise institutional settings to seize economic opportunities surrounding the transition to a green economy, and considers ways to enrich the Green Growth Strategy based on work undertaken since its launch.

  • 27-July-2015

    English

    Employment and Skills Strategies in Israel

    This report delivers evidence-based and practical recommendations on how to better support employment and economic development in Israel. It builds on sub-national data analysis and consultations with local stakeholders in Haifa and Yizreel. It provides a comparative framework to understand the role of the local level in contributing to more and better quality jobs. The report can help national and local policy makers in Israel build effective and sustainable partnerships at the local level, which join-up efforts and achieve stronger outcomes across employment, training, and economic development policies. Co-ordinated policies can help workers find suitable jobs, while also stimulating entrepreneurship and productivity, which increases the quality of life and prosperity within a community as well as throughout the country.

  • 23-July-2015

    English

    Energy Policies of IEA Countries: Spain 2015

    Since the last IEA review in 2009, Spain’s dependence on energy imports has decreased markedly, in part thanks to a rapid increase in renewable energy supply. Spain’s security of supply has further been improved with diversified import sources and enhanced storage capacity for both oil and gas.

    In the electricity sector, Spain has built a large, diverse and reliable power generation fleet. After several years of efforts, the government has now also managed to solve the massive imbalance between the electricity system’s regulated costs and revenues. The broad and deep electricity market reform has fundamentally changed the remuneration scheme for renewable energy. Spain must now maintain its strong and long-term commitment to a financially sustainable electricity system. To improve investor confidence, it should also closely follow the principles of transparency, predictability and certainty when revising policies and regulations.

    New momentum for establishing additional cross-border connections in electricity and gas will eventually enable Spain to use its large power and liquefied natural gas capacity to increase flexibility, diversity and security in the European Union internal market. The government should now focus on longer-term issues including energy demand and greenhouse gas emissions. A critical question is how to encourage the transition to a low-carbon energy system.

    This review analyses the energy policy challenges Spain faces and provides sectoral recommendations for further policy improvements. It is intended to help guide the country towards a more secure and sustainable energy future.

  • 23-July-2015

    English

    Energy Statistics of OECD Countries 2015

    This volume contains data on the supply and consumption of coal, oil, gas, electricity, heat, renewables and waste presented as comprehensive energy balances expressed in million tonnes of oil equivalent. Complete data are available for 2012 and 2013 and supply estimates are available for the most recent year (i.e. 2014). Historical tables summarise production, trade and final consumption data as well as key energy and economic indicators. The book also includes definitions of products and flows, explanatory notes on the individual country data and conversion factors from original units to energy units.

    More detailed data in original units are published in the 2015 edition of Energy Statistics of OECD Countries, the sister volume of this publication.
     

  • 23-July-2015

    English

    Energy Balances of OECD Countries 2015

    This volume contains data on energy supply and consumption in original units for coal, oil, gas, electricity, heat, renewables and waste. Complete data are available for 2012 and 2013 and supply estimates are available for the most recent year (i.e. 2014). Historical tables summarise data on production, trade and final consumption. The book also includes definitions of products and flows and explanatory notes on the individual country data.

    In the 2015 edition of Energy Balances of OECD Countries, the sister volume of this publication, the data are presented as comprehensive energy balances expressed in million tonnes of oil equivalent.

  • 15-July-2015

    English

    OECD Digital Economy Outlook 2015

    The digital economy now permeates countless aspects of the world economy, impacting sectors as varied as banking, retail, energy, transportation, education, publishing, media or health. Information and Communication Technologies are transforming the ways social interactions and personal relationships are conducted, with fixed, mobile and broadcast networks converging, and devices and objects increasingly connected to form the Internet of things.
    This report assesses how countries can maximise the potential of the digital economy as a driver for innovation and inclusive growth, and discusses the evolutions in the digital economy that policy makers need to consider as well as the emerging challenges they need to address as a part of national digital strategies. Chapters include an overview of the current status and outlook of the digital economy; the main trends in the ICT sector, and developments in communication and regulation policy; and overviews of ICT demand and adoption, plus the effects of the digital economy on growth and development. This volume also includes a chapter on developments related to trust in the digital economy and on the emerging Internet of things.

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  • 15-July-2015

    English

    Hydrogen and Fuel Cells

    Current trends in energy supply and use are patently unsustainable – economically, environmentally and socially. Without decisive action, energy-related emissions of carbon dioxide (CO2) will more than double by 2050 and increased fossil energy demand will heighten concerns over the security of supplies. We can and must change our current path. However, this will take an energy revolution and low-carbon energy technologies will have a crucial role to play. Energy efficiency, sources of renewable energy, carbon capture and storage (CCS), nuclear power and new transport technologies will all require widespread deployment if we are to achieve reductions in greenhouse gas (GHG) emissions. Every major country and sector of the economy must be involved. The task is urgent if we are to make sure that investment decisions taken now do not saddle us with sub-optimal technologies in the long term.

     

  • 14-July-2015

    English

    Multilateral Aid 2015 - Better Partnerships for a Post-2015 World

    This 2015 OECD report on multilateral aid contributes to the broader debate on how to implement the post-2015 development agenda. It argues that multilateral organisations have a fundamental role to play to forge and strengthen inclusive partnerships that will provide the collective, cross-border solutions needed to eradicate absolute poverty and foster a new era of economic progress, environmental sustainability, and peaceful and inclusive societies. But to be fit for purpose, multilateral organisations will need to implement a challenging reform agenda to both address the unfinished business of internal changes and respond to a fast-changing global environment.

    Multilateral Aid 2015 identifies how bilateral providers can support multilateral organisations in implementing the necessary changes and fostering effective partnerships that (i) make best use of all resources available for development, including earmarked funding, and (ii) leverage knowledge and resources from partners beyond the “traditional donors”.

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