Current Developments/Activities on the Safety of Manufactured Nanomaterials

26-mai-2011

This document provides a snapshot of information on current/planned activities related to the safety of manufactured nanomaterials in OECD member countries and other delegations that attended the 8th meeting of OECD’s Working Party on Manufactured Nanomaterials (Paris France, 16-18 March 2011). There are also written reports on current activities from other International Organisations such as the ISO, the FAO and the WHO.

PESTICIDES: Guidance Document on the Planning and Implementation of Joint Reviews of Pesticides

20-mai-2011

A joint review is an evaluation of a pesticide dossier through work-sharing among countries. The participating regulatory authorities review the work of the primary reviewers for each particular science discipline, and the end product is used by all participating countries as the basis for regulatory decisions. This guidance document was prepared to support joint reviews to maximize opportunities of work-sharing. This guidance document includes two main phases of a joint review, planning and implementation phases, to help industries and regulatory authorities conduct the joint review process.

QSAR Toolbox: New training material available

18-mai-2011

A first batch of training material for version 2 of the Toolbox is now available. The QSAR Toolbox is a software application intended to be used by governments, industry and other stakeholders to fill gaps in (eco)toxicity data needed for assessing the hazards of chemicals. This first batch of training material is focused on familiarizing beginners with the workflow of the Toolbox, by guiding them in a step-by-step manner through a number of examples.

Brazil: joins OECD agreement on mutual acceptance of chemical safety data

05-mai-2011

Brazil has become the fourth key emerging economy to join the OECD system for the Mutual Acceptance of Data (MAD) in the Assessment of Chemicals, ensuring that the results of non-clinical chemical safety testing done there will be accepted in all other participating countries.

QSAR Toolbox: Guidance on importing databases

03-mai-2011

A guidance document for importing databases into the OECD QSAR Toolbox is now available. The QSAR Toolbox is a software application intended to be used by governments, industry and other stakeholders to fill gaps in (eco)toxicity data needed for assessing the hazards of chemicals. This new document specifically provides guidance on how users can import their own proprietary experimental data into the Toolbox and use them to fill data gaps by read-across or trend analysis.

Update of OECD Harmonised Templates

29-avr.-2011

The OECD Harmonised Templates (OHT) are standard data formats for reporting studies done on chemicals to determine their properties or effects on human health and the environment. Minor updates were recently made to 37 OHTs, based on the experience and suggestions for improvement from users implementing them in databases such as IUCLID 5.3 (managed by the European Chemical Agency).

Details of additions brought or changes made in February 2011 in these templates and associated XML files are accessible on the OHTs Webpage, “Update Overview ” link.

Report on Structural Alerts for the Identification of Protein-Binding Chemicals now published

11-avr.-2011

This document is a report of the expert consultation held on 20 October 2010 with the aim to evaluate a set of structural alerts for estimating covalent binding of chemicals with proteins. The resulting set of alerts have been implemented in version 2.0 of the OECD QSAR Toolbox.

PRTR: Summary of Estimation Techniques for Releases from Products is now available

07-avr.-2011

The release of chemicals used in products is one of the key area where better knowledge is needed for a sound risk assessment and management of chemicals. OECD has just published a summary of estimation techniques for releases from products. This document outlines currently available techniques for quantifying releases of chemicals to the environment from the use phase of end-products. It also includes 11 case studies which target specific substances (e.g. lead) and product types (e.g. building and car care products and packages).

India: joins OECD agreement on mutual acceptance of chemical safety data

06-avr.-2011

India has become the third key emerging economy to join the OECD system for the Mutual Acceptance of Data (MAD) in the Assessment of Chemicals, ensuring that the results of non-clinical chemical safety testing done there will be accepted in all other participating countries

Estimates for dissociation constant now available in the OECD QSAR Toolbox

29-mars-2011

One of the major new features in version 2.1 of the OECD QSAR Toolbox is the availability of estimates of pKa for more than 100000 chemicals. Following an agreement with the company ChemAxon, pKa estimates have been generated with Chemaxon’s pKa calculator  and stored in the Toolbox. The availability of these estimates will greatly enhance the potential of the Toolbox to predict the behaviour of chemicals in the environment as well as their effects in animals and humans.