Latest Documents


7-June-2010

English, , 4,766kb

Report of the Expert Consultation on Scientific and Regulatory Evaluation of Organic Chemistry Mechanism-Based Structural Alerts for the Identification of DNA Binding Chemicals (part 2)

This document is a report of the expert consultation held on 20 October 2009 with the aim to evaluate a set of structural alerts for estimating covalent binding of chemicals with DNA.

1-June-2010

English, , 170kb

The Pov and LRTP Screening Tool Brochure

Estimating overall persistence and long-range transport potential of organic chemicals.

1-June-2010

English

OECD Pov and LRTP Screening Tool

A software in a spreadsheet format containing multimedia chemical fate models to estimate overall persistence and long-range transport potential.

8-December-2009

English

Manual for the Assessment of Chemicals

Revised Manual for the Assessment of Chemicals: Table of Contents

4-December-2009

English

Published Assessments

This is a page indicates where Final SIDS Documents including the SIDS Inital Assessment Profile (SIAP), SIDS Initial Assessment Reports (SIARS), SIDS Dossiers and IUCLID export files can be found.

18-June-2009

English

Grouping of Chemicals: Chemical Categories and Read-Across

A chemical category is a group of chemicals whose physicochemical and human health and/or ecotoxicological properties and/or environmental fate properties are likely to be similar or follow a regular pattern, usually as a result of structural similarity.

4-June-2009

English

OECD QSAR Toolbox: Frequently Asked Questions

The Toolbox is a software application intended to be used by governments, chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals. The Toolbox incorporates information and tools from various sources into a logical workflow. Crucial to this workflow is grouping chemicals into chemical categories.

4-June-2009

English

Validation of (Q)SAR Models

The Toolbox is a software application intended to be used by governments, chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals. The Toolbox incorporates information and tools from various sources into a logical workflow. Crucial to this workflow is grouping chemicals into chemical categories.

4-June-2009

English

History of the OECD (Q)SAR Project

International co-operation among OECD member countries on (Q)SARs started in the early 1990s. The objective of the OECD (Q)SAR project is to facilitate practical application of (Q)SAR approaches in regulatory contexts by governments and industry and to improve their regulatory acceptance.

4-May-2009

English

Introduction to (Quantitative) Structure Activity Relationships

Structure-Activity Relationship (SAR) is an approach designed to find relationships between chemical structure (or structural-related properties) and biological activity (or target property) of studied compounds. As such it is the concept of linking chemical structure to a chemical property (e.g., water solubility) or biological activity including toxicity (e.g., fish acute mortality). Qualitative SARs and quantitative SARs,

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