Latest Documents


  • 31-October-2016

    English

    Draft Guidance and Review Documents/Monographs

    The Draft Guidance Document on Good In Vitro Method Practices (Givimp) for the Development and Implementation of In Vitro Methods for Regulatory Use in Human Safety Assessment is open for public comments until 16 December 2016.

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  • 18-October-2016

    English

    Developmental neurotoxicity: OECD/EFSA experts discuss non-animal test methods

    Participants from 15 countries attended the Workshop on Developmental Neurotoxicity: The use of non-animal test methods for regulatory purposes” on 18 October 2016, in Belgium. The event, co-organised by the OECD and the European Food Safety Authority (EFSA), focused on opportunities and challenges related to alternative methods for testing and assessing the DNT potential of chemicals.

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  • 20-September-2016

    English

    OECD publishes new and updated Test Guidelines for effects on human health and on environmental species

    The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. Every year new and updated Test Guidelines are adopted to meet the regulatory needs in OECD member countries. The most recent Test Guidelines were adopted in July 2016.

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  • 2-September-2016

    English

    Section 4: Health Effects

    New deadlines for comments: Draft updated TG 492 on RhCE for eye hazard potential and draft updated performance standards for the validation of similar methods. The deadline for public comments of 3 October 2016.

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  • 27-June-2016

    English

    Draft documents for public comments

    This page contains a list of the Guidelines for the Testing of Chemicals.

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  • 25-April-2016

    English

    Application of Good Laboratory Practice Principles to Computerised Systems

    This new Advisory Document replaces the 1995 consensus document on the Application of the Principles of GLP to Computerised Systems. It retains all of the key text from the original 1995 document, but includes new text to reflect the current state-of-the art in this field.

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  • 18-March-2016

    English, PDF, 1,601kb

    Draft Guidance Document on IATA for Eye Hazard Potential

    The objective of the present Guidance Document (GD) is to establish an Integrated 2 Approach to Testing and Assessment (IATA) for hazard identification of serious eye 3 damage and eye irritation potential of test chemicals (or the absence thereof) that 4 provides adequate information for classification and labelling according to the United 5 Nations Globally Harmonised System (UN GHS, 2015).

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  • 3-February-2016

    English

    Avian Toxicity Testing

    This work describes the various endeavours of OECD countries to develop harmonised methodologies for birds toxicity testing, including the successful outcomes or the reasons for stopping activities in some cases. The work has required commitment from countries and industry in terms of staffing and laboratory resources to perform experimental testing and generate data.

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  • 7-January-2016

    English

    Substitution of hazardous chemicals

    A new report has been launched by the OECD Ad Hoc Group on Substitution of Harmful Chemicals. The report identifies where gaps remain in terms of possible missing tools, guidance and research to support stakeholders engaged in alternatives assessment and substitution of harmful chemicals.

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  • 28-July-2015

    English, PDF, 771kb

    Draft Updated Test Guideline 223: Avian Acute Oral Toxicity Test

    This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test.

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