Latest Documents


  • 25-April-2016

    English

    Application of Good Laboratory Practice Principles to Computerised Systems

    This new Advisory Document replaces the 1995 consensus document on the Application of the Principles of GLP to Computerised Systems. It retains all of the key text from the original 1995 document, but includes new text to reflect the current state-of-the art in this field.

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  • 1-April-2016

    English

    Draft Guidance and Review Documents/Monographs

    Open for public comment until 13 May 2016, the Guidance Document establishing an Integrated Approach to Testing and Assessment (IATA) for hazard identification of serious eye damage and eye irritation potential of test chemicals aims to provide adequate information for classification and labelling according to the United Nations Globally Harmonised System.

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  • 18-March-2016

    English, PDF, 1,601kb

    Draft Guidance Document on IATA for Eye Hazard Potential

    The objective of the present Guidance Document (GD) is to establish an Integrated 2 Approach to Testing and Assessment (IATA) for hazard identification of serious eye 3 damage and eye irritation potential of test chemicals (or the absence thereof) that 4 provides adequate information for classification and labelling according to the United 5 Nations Globally Harmonised System (UN GHS, 2015).

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  • 23-February-2016

    English

    Section 2: Effects on Biotic Systems

    This is a list of the Guidelines for the Testing of Chemicals in Section 2: Effects on Biotic Systems

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  • 3-February-2016

    English

    Avian Toxicity Testing

    This work describes the various endeavours of OECD countries to develop harmonised methodologies for birds toxicity testing, including the successful outcomes or the reasons for stopping activities in some cases. The work has required commitment from countries and industry in terms of staffing and laboratory resources to perform experimental testing and generate data.

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  • 8-January-2016

    English

    Section 4: Health Effects

    New deadlines for comments: Test Guidelines (TG) 402 on Acute Dermal Toxicity and scoping document; Draft updated TG 412 on 28-d repeated dose inhalation toxicity study; Draft updated TG 413 on 90-d repeated dose inhalation; Draft revised TG 438 on Isolated Chicken eye test document toxicity study and Supporting document for amending Decision Criteria in TG 438.

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  • 28-July-2015

    English, PDF, 771kb

    Draft Updated Test Guideline 223: Avian Acute Oral Toxicity Test

    This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test.

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  • 15-June-2015

    English, PDF, 184kb

    Draft Updated Test Guideline 232: Collembolan Reproduction Test in Soil

    This Test Guideline is designed for assessing the effects of chemicals on the reproductive output of the collembolans in soil. It is based on existing procedures (1) (2). The parthenogenetic Folsomia candida and sexually reproducing Folsomia fimetaria are two of the most accessible species of Collembola, and they are culturable and commercially available.

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  • 16-February-2015

    English

    Expansion of Brazil's scope under OECD agreement on mutual acceptance of chemical safety data

    In 2011, Brazil joined OECD’s Mutual Acceptance of Data (MAD) system ensuring that its chemical safety test data will be accepted by all 40 countries adhering to MAD. Originally limited to data developed in Brazil on pesticides, biocides and industrial chemicals, it now also includes veterinary products, feed additives, cosmetics, pharmaceutical products, sanitizers, wood preservative and treatments of effluents and natural ecosystems.

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  • 6-February-2015

    English

    Launch of 2 OECD Test Guidelines on human hazard endpoint skin sensitisation

    The OECD has just published two new Test Guidelines on human health hazard endpoint skin sensitisation. Skin sensitisation refers to an allergic response following skin contact with the tested chemical, as defined by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS).

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