This document presents a review of fish toxicity testing for the regulatory purpose
of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is
also considered where relevant. A review of regulatory needs for fish tests under
various jurisdictions in OECD countries is provided in Chapter 2, followed by a review
of statistical issues and general test considerations in Chapters 3 and 4, respectively.
The document examines animal welfare concerns and alternatives to fish tests in Chapter
5. Chapter 6 provides a systematic review of existing and draft OECD Guidelines which
use fish for toxicity or bioaccumulation studies. Finally Chapter 7 describes a generic
framework for assessing the environmental hazards of chemicals using fish tests in
the most efficient way. An Annex contains conclusions and recommendations made and
agreed at the workshop in September 2010. The recommendations concern, among other
aspects, possible improvements to existing Test Guidelines, development of guidance
on specific issues, harmonisation of existing Test Guidelines for common issues, development
of new Test Guidelines, and proposals for deletion of outdated Test Guidelines.