Latest Documents


  • 4-June-2009

    English

    History of the OECD (Q)SAR Project

    International co-operation among OECD member countries on (Q)SARs started in the early 1990s. The objective of the OECD (Q)SAR project is to facilitate practical application of (Q)SAR approaches in regulatory contexts by governments and industry and to improve their regulatory acceptance.

  • 4-May-2009

    English

    Introduction to (Quantitative) Structure Activity Relationships

    Structure-Activity Relationship (SAR) is an approach designed to find relationships between chemical structure (or structural-related properties) and biological activity (or target property) of studied compounds. As such it is the concept of linking chemical structure to a chemical property (e.g., water solubility) or biological activity including toxicity (e.g., fish acute mortality). Qualitative SARs and quantitative SARs,

  • 30-January-2009

    English, , 858kb

    Data Analysis of the Identification of Correlations between Polymer Characteristics and Potential for Health or Ecotoxicological Concern

    This document contains an analysis of data on 205 polymers to identify correlations between polymer characteristics and the potential for health or ecotoxicological concern.

  • 15-avril-2008

    Français

    L’OCDE aide les gouvernements et l’industrie à consacrer moins d’argent et de temps aux essais de produits chimiques tout en réduisant l’expérimentation animale

    L’OCDE vient de mettre au point un instrument novateur, la Boîte à outils sur les applications des (Q)SAR, pour évaluer les propriétés dangereuses des produits chimiques en analysant leur structure moléculaire.

    Also Available
  • 27-September-2007

    English

    Guidance on Grouping of Chemicals

    Revised Guidance for Grouping of Chemicals. Considers closely related chemicals as a group, or cateogory, rather than as individual chemicals. In this approach, not every chemical needs to be tested for every endpoint.

  • 3-August-2007

    English

    Electronic Tools for Data Submission, Evaluation and Exchange in the OECD Cooperative Chemicals Assessment Programme

    The main electronic tool for data submission, evaluation and exchange used in the OECD Cooperative Chemicals Assessment Programme is the International Uniform Chemical Information Database (IUCLID). IUCLID is a software program for the administration of data on chemical substances.

  • 1-August-2007

    English

    OECD Harmonised Templates

    The OECD Harmonised Templates are standard data formats for reporting reults of studies with chemicals in order to determine their properties and effects on human health and the environment.

  • 4-May-2007

    English, Excel, 544kb

    Brochure on eChemPortal: The Global Portal to Information on Chemical Substances

    This brochure provides details on the project for eChemPortal: The Global Portal to Information on Chemical Substances. eChemPortal is an internet gateway that provides direct free access to information on the properties of chemicals (physical-chemical properties, environmental fate and behaviour, ecotoxicity, toxicity) as well as to hazard and risk assessments. It allows users to simultaneously search for chemicals contained in

  • 15-février-2007

    Français, , 1,105kb

    Guidance Document on the Validation of (quantitative) Structure-activity Relationship [(Q)SAR] Models

    The reader will find that transparency in the validation process and objective determination of the reliability of (Q)SAR models are crucial to extending the regulatory acceptance of (Q)SAR models.<SPAN style="mso-spacerun:

  • 15-February-2007

    English, , 553kb

    Report on the Regulatory Uses and Applications in OECD Member Countries of Quantitative Structure-Activity Relationships (Q)SAR Models in the Assessment of New and Existing Chemicals

    This case studies report is part of the OECD effort to develop guidance for regulatory applications of (Quantitative) Structure-Activity Relationship [(Q)SAR] models, and emphasizes the use of programme-specific case studies.

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