Published Assessments

This is a page indicates where Final SIDS Documents including the SIDS Inital Assessment Profile (SIAP), SIDS Initial Assessment Reports (SIARS), SIDS Dossiers and IUCLID export files can be found.

Grouping of Chemicals: Chemical Categories and Read-Across

A chemical category is a group of chemicals whose physicochemical and human health and/or ecotoxicological properties and/or environmental fate properties are likely to be similar or follow a regular pattern, usually as a result of structural similarity.

OECD QSAR Toolbox: Frequently Asked Questions

The Toolbox is a software application intended to be used by governments, chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals. The Toolbox incorporates information and tools from various sources into a logical workflow. Crucial to this workflow is grouping chemicals into chemical categories.

Validation of (Q)SAR Models

The Toolbox is a software application intended to be used by governments, chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals. The Toolbox incorporates information and tools from various sources into a logical workflow. Crucial to this workflow is grouping chemicals into chemical categories.

History of the OECD (Q)SAR Project

International co-operation among OECD member countries on (Q)SARs started in the early 1990s. The objective of the OECD (Q)SAR project is to facilitate practical application of (Q)SAR approaches in regulatory contexts by governments and industry and to improve their regulatory acceptance.

Introduction to (Quantitative) Structure Activity Relationships

Structure-Activity Relationship (SAR) is an approach designed to find relationships between chemical structure (or structural-related properties) and biological activity (or target property) of studied compounds. As such it is the concept of linking chemical structure to a chemical property (e.g., water solubility) or biological activity including toxicity (e.g., fish acute mortality). Qualitative SARs and quantitative SARs,

Data Analysis of the Identification of Correlations between Polymer Characteristics and Potential for Health or Ecotoxicological Concern

This document contains an analysis of data on 205 polymers to identify correlations between polymer characteristics and the potential for health or ecotoxicological concern.

L’OCDE aide les gouvernements et l’industrie à consacrer moins d’argent et de temps aux essais de produits chimiques tout en réduisant l’expérimentation animale

L’OCDE vient de mettre au point un instrument novateur, la Boîte à outils sur les applications des (Q)SAR, pour évaluer les propriétés dangereuses des produits chimiques en analysant leur structure moléculaire.

Also Available

• OECD helps governments and industry save money, time and animals for chemical tests

Guidance on Grouping of Chemicals

Revised Guidance for Grouping of Chemicals. Considers closely related chemicals as a group, or cateogory, rather than as individual chemicals. In this approach, not every chemical needs to be tested for every endpoint.

Electronic Tools for Data Submission, Evaluation and Exchange in the OECD Cooperative Chemicals Assessment Programme

The main electronic tool for data submission, evaluation and exchange used in the OECD Cooperative Chemicals Assessment Programme is the International Uniform Chemical Information Database (IUCLID). IUCLID is a software program for the administration of data on chemical substances.