Structure-Activity Relationship (SAR) is an approach designed to find relationships between chemical structure (or structural-related properties) and biological activity (or target property) of studied compounds. As such it is the concept of linking chemical structure to a chemical property (e.g., water solubility) or biological activity including toxicity (e.g., fish acute mortality). Qualitative SARs and quantitative SARs,
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This report provides preliminary analyses and recommendations as well as brief summaries of background documen
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As part of the OECD activities to promote international co-operation in addressing human health and environmental safety aspects of manufactured nanomaterials, the OECD has developed a global resource which details research projects that address safety issues of manufactured nanomaterials. This database holds details of completed, current and planned research projects on safety, which are to be updated and managed electronically by
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This document contains an analysis of data on 205 polymers to identify correlations between polymer characteristics and the potential for health or ecotoxicological concern.
OECD’s Working Party on Manufactured Nanomaterials (WPMN) launched a Sponsorship Programme in November 2007. The programme involves OECD member countries, as well as some non-member economies and other stakeholders to pool expertise and to fund the safety testing of specific Manufactured Nanomaterials (MNs). In launching this Sponsorship Programme, the WPMN agreed on a priority list of 13 MNs for testing (based on materials which are
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The Nanoscale Materials Stewardship Program (NMSP) was developed to help provide a firmer scientific foundation for regulatory decisions by encouraging submission and development of information for nanoscale materials. The NMSP comprised two sub-programs, the Basic Program and the In-Depth Program. When the NMSP was initiated, EPA committed to issue this interim report after one year. The Agency welcomes comments on this interim
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The Pesticides Programme has undertaken work to: (i) identify and overcome obstacles to work-sharing; (ii) harmonise data requirements and test guidelines; and (iii) harmonise hazard/risk assessment approaches.
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This guidance document focuses on microbiological efficacy testing. It covers efficacy testing of articles treated with antimicrobials in the manufacturing process with the intention of the achieving an external effect.
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The world is rapidly transforming and a number of dynamic emerging economies,including South Africa, have become major players and trading partners with the members of the Organisation for Economic Co-operation and Development(OECD). In this context, the OECD Members have recognised the need for theOrganisation to become more open and relevant in order to realise its strategicgoal of becoming an important hub for dialogue on globally
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This report presents the results of an OECD seminar on ways to achieve risk reduction while addressing issues associated with the use of chemical pesticides or non-chemical means of crop protection on a small scale.