The OECD is pleased to announce, together with the U.S Environmental Protection Agency and the European Commission Joint Research Centre, the Adverse Outcome Pathway Knowledge Base (AOP KB). This is a web-based platform which aims to bring together all the knowledge on how chemicals can induce adverse effects, therefore providing a focal point for AOP development and dissemination.
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Une approche coopérative globale de la réglementation des pesticides agricoles et de la lutte contre les ravageurs compatible avec le développement durable
Ce rapport présente les résultats d’une étude sur les Régimes Réglementaires des Nanomatériaux Manufacturés dans diverses juridictions de l’OCDE, avec une attention particulière orientée vers les défis réglementaires futurs et la collaboration entre les pays.
Ce document concerne un atelier sur l’exposition des enfants aux produits chimiques qui s’est tenu le 7-8 octobre 2013, Utrecht, Pays bas. Les principaux résultats sont : 1) un arbre décisionnel pour aider les évaluateurs à savoir quand réaliser des études d’évaluation du risque et de l’exposition des enfants ; et 2) des recommandations pour des travaux de recherche sur des questions spécifiques de l’évaluation de l’exposition. 
This document describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations, such as obesity/diabetes/metabolic syndrome, reproductive dysfunction, and neuro-developmental abnormalities. Assays and endpoints are described that could be used in new or existing OECD Test Guidelines for evaluating chemicals for endocrine-disrupting activity. Endocrine pathways evaluated are the hypothalamus:pituitary:adrenocortical (HPA) axis, the hypothalamus:pituitary:gonad (HPG) axis, the somatotropic axis, the retinoid signaling pathway, the hypothalamus:pituitary:thyroid (HPT) axis, the vitamin D signaling pathway, and the peroxisome proliferator-activated receptor (PPAR) signaling pathway.
This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.
This document is the report of the OECD Seminar on Risk Reduction through Prevention, Detection and Control of the Illegal International Trade in Agricultural Pesticides that took place on 19 May, 2010 at OECD, Paris, France, and was chaired by Dr. Wolfgang Zornbach of the German Federal Ministry of Food, Agriculture and Consumer Protection. After a series of presentations on governments‟ and other stakeholders‟ approaches and experiences (copies of all presentations are in Annex 4), the Seminar discussed the various issues associated with the illegal international trade of pesticides: risks and consequences of using illegal pesticides, risks linked to the pesticide supply/logistical chain, existing systems in place in countries, difficulties faced by authorities and customs, etc. The Seminar developed a set of recommendations targeted at governments, industry, all stakeholders and OECD.
This document is the report of the “OECD Workshop on Integrated Pest Management (IPM) -
Strategies for the adoption and implementation of IPM in agriculture contributing to the sustainable use of
pesticides and to pesticide risk reduction”, that took place on 16 19 October 2011, in Berlin, Germany, and
was chaired by Dr. Wolfgang Zornbach of the German Federal Ministry of Food, Agriculture and
The developed detailed recommendations for promoting and facilitating the adoption and implementation of IPM strategies and for encouraging appropriate stakeholders to use IPM tools and measures. The workshop was planned in the framework of the “OECD Strategic Approach in Pesticide Risk Reduction”. It addressed the following four main issues: technology and Information, economics and market access, policies and strategies and measurements and impact. This report includes the outcomes of the workshop discussions, as well as the overall workshop conclusions (Section 4) and recommendations (Section 5) targeted at governments, all stakeholders and OECD.
This report of a survey collates member countries’ approaches to manage and mitigate the risk of pesticide use near residential areas.
OECD has published a report of a survey that provides information and recommendations on how to deal with stocks of “obsolete” pesticides in OECD member (and partner) countries. Such pesticides’ obsolescence can arise for a number of reasons including product deterioration, product de-registration, and product revision.