Essais des produits chimiques

Series on Testing and Assessment: Testing for Human Health

 

No. 180: Streamlined Summary Document Related to the Fluorescein Leakage (Fl) Test Method for Identification of Ocular Corrosives and Severe Irritants (TG 460) 

No. 176: Report on The Retrospective Analysis of 2-Generation Reprotoxicity Data

No. 168: The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins: Part 1Part 2

No. 163:  Peer Review Report Related to Three Cell Transformation Assays and Agreement of the Working Group of the National Coordinators of the Test Guidelines Programme on the Follow-Up to the Peer Review

No 161: Peer Review Report for the Validation of the Stably Transfected Transcriptional Activation Assay for the Detection Androgenic and Anti-Androgenic Activity of Chemicals (2011)

No 160: Guidance Document on the Bovine Corneal Opacity and Permeability (Bcop) and Isolated Chicken Eye (Ice) Test Methods: Collection of Tissues for Histological Evaluation and Collection of Data on Non-Severe Irritants

No 159: Validation Report for the Skin Irritation Test Method Using LabCyte EPI-MODEL24

No 156: Guidance Notes on Dermal Absorption

No 155: Peer Review Report of the Validation of The Skin Irritation Test Using Labcyte Epi-Model 24

No 153: Guidance Document for the Derivation of an Acute Reference Concentration (Arfc)

No. 151: Guidance Document Supporting OECD Test Guideline 443 on the Extended One-Generation Reproductive Toxicity Test

No.149: Validation Report of the Balb/c 3T3 Cell Transformation Assay (2011)

No. 147: Syrian Hamster Embryonic (SHE) Cell PH 7.0 Cell Transformation Assay Prevalidation Study Report (2011)

No. 146: Syrian Hamster Embryonic (SHE) Cell PH 6.7 Cell Transformation Assay Prevalidation Study Report (2011)

No 145: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays: Retrospective Performance Assessment
No 137: Explanatory Background Document to the OECD Test Guideline on In Vitro Skin Irritation Testing

No 133: Peer Review Report for the H295R Cell-Based Assay for Steroidogenesis

No 132: Report of the Multi-Laboratory Validation of the H295R Steroidogenesis Assay to Identify Modulators

No 129: Guidance Document on Using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systematic Toxicity Tests

No 125: Guidance Document on Histopathology for Inhalation Toxicity Studies, Supporting TG 412 (Subacute Inhalation Toxicity: 28-day Study) and TG 413 (Subchronic Inhalation Toxicity: 90-day Study)

No 124: Guidance for the Derivation of an Acute Reference Dose

No 117: Guidance Document 117 on the Current Implementation of Internal Triggers in Test Guideline 443 for an Extended One Generation Reproductive Toxicity Study, in the United States and Canada

No 116: Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 - Second edition (2011)

No 115: Guidance Document on the Weanling Hershberger Bioassay in Rats: A Short-term Screening Assay for (Anti) Androgenic Properties

No 114: Performance Assessment of Different Cytotoxic and Ctyostatic Measures for the In Vitro Micronucleus Test (MNVIT): Summary of Results in the Collaborative Trial

No 110: Report of the Validation Peer Review for the Weanling Hershberger Bioassay and Agreement of the Working of National Coordinators of the Test Guidelines Programme on the Follow-up of this Report

No 108: Report of the Validation of the Hershberger Bioassay (Weanling Model)

No 106: Guidance Document for Histologic Evaluation of Endocrine and Reproductive Tests in Rodents 

Part 2

Part 3 (section 1)

Part 3 (section 2)

Part 3 (section 3)

Part 3 (section 4)

Part 3 (section 5)

Part 4

Part 5

Part 6

No 105: Report on Biostatistical Performance Assessment of the Draft TG 436 Acute Toxic Class Testing Method for Acute Inhalation Toxicity

No 104: Performance Assessment: Comparison of 403 and CXT Protocols via Simulation and for Selected Real Data Sets

No 103: Detailed Review Paper on Transgenic Rodent Mutation Assays - Annexes

No 103: Detailed Review Paper on Transgenic Rodent Mutation Assays

No 90: Background Review Document on the Rodent Hershberger Bioassay

No 89: Retrospective Performance Assessment of the Test Guideline 426 on Developmental Neurotoxicity

No 86: Report of the OECD Validation of the Rodent Hershberger Bioassay - Phase 2: Testing of Androgen Agonists, Androgen Antagonists and a 5 α-Reductase Inhibitor in Dose Response Studies by Multiple Laboratories

No 85: Report of the Validation Peer Review for the Hershberger Bioassay, and the Agreement of the Working Group of the National Coordinators of the Test Guidelines Programme on the Follow-up of this Report

No 83: Summary Report of the Peer Review Panel on the Stably Transfected Transcriptional Activation Assay for Detecting Estrogenic Activity of Chemicals, and Agreement of the Working Group of National Coordinators of Test Guidelines Programme on the Follow-up of this Report

No 81: Summary Report of the Validation Peer Review for the Updated Test Guideline 407, and Agreement of the Working Group of the National Coordinators of the Test Guidelines Programme on the Follow-up of this Report

No 73: Report of the Validation of the Rat Hershberger Assay - Phase 3: Coded Testing of Androgen Agonists, Androgen Antagonists and Negative Reference Chemicals by Multiple Laborotories. Surgical Castrate Model Protocol.

No 71: Guidance Document on the Uterothrophic Bioassay - Procedure to Test for Antioestrogenicity

Link to the Korean Version of No 71

No 68: Summary Report of the Uterothropic Bioassay Peer Review Panel, including Assessmenf of the Working Group of the National Coordinators of the Test Guidelines Programme on the Follow-up of this Report

No 67: Report of the Uterotrophic Bioassay: Additional Data Supporting the Test Guideline on the Uterotrophic Bioassay in Rodents

No 66: OECD Report of the Validation of the Rodent Uterotrophic Bioassay - Phase 2: Testing of Potent and Weak Oestrogen Agonists by Multiple Laboratories

No 65: OECD Report of the Initial Work Towards the Validation of the Rodent Uterothophic Assay - Phase 1

No 62: Final OECD Report of the Initial Work Towards the Validation of the Rat Hershberger Assay - Phase 1: Androgenic Response to Testosterone Propionate, and Anti-Androgenic Effects of Flutamide

No 59: Report of the Validation of the Updated Test Guideline 407 - Repeat Dose 28-day Oral Toxicity Study in Laboratory Rats [Annexes]

No 57: Detailed Review Paper on Thyroid Hormone Disruption Assays

No 39: Guidance Document on Acute Inhalation Toxicity Testing

No 43: Guidance Document on Mammalian Reproductive Toxicity Testing and Assessment

No 35: Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies

No 38: Detailed Background Review of the Uterotrophic Bioassay [References]

No 34: Guidance Document on the Validation and International Acceptance of New or Updated Test Methods for Hazard Assessment

No 32: Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies

No 31: Detailed Review Paper on Cell Transformation Assays for Detection of Chemical Carcinogens

No 28: Guidance Document for the Conduct of Skin Absorption Studies

No 24: Guidance Document on Acute Oral Toxicity Testing

No 20: Guidance Document for Neurotoxicity Testing

No 19: Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Humane Endpoints

ENV Monograph No 36: Scientific Criteria for Validation of In Vitro Toxicity Tests

Pages 1-31

Paged 32-62

This publication is also availabile in French: Part 1Part 2

 

 

 

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