Essais des produits chimiques



General Documents:

No 198: Report on statistical issues related to OECD test guidelines (tgs) on genotoxicity


In vitro

TG 471: Bacterial reverse mutation test (1997)
TG 473: In vitro mammalian chromosome aberration test (2014)
TG 476: In vitro mammalian cell gene mutation test (1997)
TG 479: In vitro sister chromatid exchange assay in mammalian cells (deleted 2 April 2014)
TG 481: Saacharomyces cerevisiae, miotic recombination assay
TG 482: DNA damage and repair, unscheduled DNA synthesis in mammalian cells in vitro (deleted 2 April 2014)

TG 487: In vitro mammalian cell micronucleus test (2014)
•    No 114: Performance assessment of different cytotoxic and ctyostatic measures for the in vitro micronucleus test (MNVIT):
                     Summary of results in the collaborative trial

No 208
: BHAS 42 cell transformation assay validation study report

In vivo

TG 474: Mammalian erythrocyte micronucleus test (2014)
TG 475: Mammalian bone marrow chromosome aberration test (2014)
TG 477: Sex-linked recessive lethal test in drosophila melanogaster (deleted 2 April 2014)
TG 478: Rodent dominant lethal test (1984)
TG 480: Saccharomyces cerevisiae, gene mutation assay (deleted 2 April 2014)
TG 483: Mammalian spermatogonial chromosome aberration test (1997)
TG 484: Mouse spot test (deleted 2 April 2014)
TG 485: Mouse heritable translocation assay (1986)
TG 486: Unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo (1997)

TG 488: Transgenic rodent somatic and germ cell gene mutation assays (2013)
•    No 103: Detailed review paper on transgenic rodent mutation assays
•    No 145: Transgenic rodent somatic and germ cell gene mutation assays: Retrospective performance assessment


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