Publications & Documents


  • 29-July-2016

    English

    Test No. 442E: In Vitro Skin Sensitisation - Human Cell Line Activation Test (h-CLAT)

    The present Test Guideline addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. Skin sensitisation refers to an allergic response following skin contact with the tested chemical, as defined by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS). This Test Guideline (TG) provides an in vitro procedure (the human cell Line Activation Test h-CLAT method) used for supporting the discrimination between skin sensitisers and non-sensitisers in accordance with the UN GHS. The h-CLAT method is proposed to address the third key event of the skin sensitisation AOP by quantifying changes in the expression of cell surface markers associated with the process of activation of monocytes and dendritic cells (DC) (i.e. CD86 and CD54), in the human monocytic leukaemia cell line THP-1, following exposure to sensitising test chemical. These surface molecules are typical markers of monocytic THP-1 activation and may mimic DC activation, which plays a critical role in T-cell priming. The changes of surface marker expression are measured by flow cytometry following cell staining with fluorochrome-tagged antibodies. The relative fluorescence intensity of surface markers compared to solvent/vehicle control are calculated and used in the prediction model, to support the discrimination between sensitisers and non-sensitisers.

  • 21-July-2016

    English

    OECD Environmental Performance Reviews: Chile 2016

    OECD Environmental Performance Reviews provide independent assessments of countries’ progress towards their environmental policy objectives. Reviews promote peer learning, enhance government accountability, and provide targeted recommendations aimed at improving environmental performance, individually and collectively. They are supported by a broad range of economic and environmental data, and evidence-based analysis. Each cycle of Environmental Performance Reviews covers all OECD countries and selected partner economies.

    This report is the second Environmental Performance Review of Chile. It evaluates progress towards sustainable development and green growth, with a focus on climate change and biodiversity conservation and sustainable use.

  • 21-July-2016

    English

    Chile must implement measures to stem environmental pressures

    Chile has taken steps to address the rising environmental pressures from its rapid economic growth, strengthening its environmental institutions and introducing new instruments, including a carbon tax. It now needs to move ahead and thoroughly implement policy measures to stem the threat to its land, air and water, according to a new OECD report.

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  • 19-July-2016

    English

    Israel's Green Tax on Cars - Environment Policy Paper

    Israel’s growing population and rising incomes have seen consumption increase substantially, bringing with it considerable pressure on the environment. One of the main environmental pressures is from the ever-increasing transport activity, especially the use of private vehicles. Although travelling in a private vehicle brings benefits to the individual using it, this entails costs to society as a whole.

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  • 12-July-2016

    English

    Aid to the Energy Generation and Supply sector

    The DAC defines aid to Energy generation and supply as including energy sector policy, planning and programmes, and aid to power generation of both renewable and non-renewable sources.

  • 11-July-2016

    English

    France will need further effort to meet environmental goals

    France has improved its environmental performance over the last decade, lowering greenhouse gas emissions, reducing some air pollutants and cutting its use of fresh water. Further effort will be needed, however, to reduce pollution by nitrates and pesticides and meet ambitious renewable energy targets, according to a new OECD report.

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  • 11-July-2016

    English

    France will need further effort to meet environmental goals

    France has improved its environmental performance over the last decade, lowering greenhouse gas emissions, reducing some air pollutants and cutting its use of fresh water. Further effort will be needed, however, to reduce pollution by nitrates and pesticides and meet ambitious renewable energy targets, according to a new OECD report.

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  • 8-July-2016

    English

    Database on instruments used for environmental policy

    This database provides information on environmentally related taxes, fees and charges, tradable permit systems, deposit refund systems, environmentally motivated subsidies and voluntary approaches used in environmental policy in OECD member countries and a number of other countries. Developed in co-operation between the OECD and the European Environment Agency.

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  • 4-July-2016

    English

    Remarks at Petersberg Climate Dialogue VII: "Making the Paris Agreement a Reality"

    Choices made today about the types, features and location of long-lived infrastructure will define the emissions profile and impact for a whole generation. Thus, starting today, as we move to adapt policies towards lower greenhouse gas emissions and climate resilient development, we must ensure that our approach is cohesive and takes a whole-of-government perspective.

  • 4-July-2016

    English

    Mr. Angel Gurría, Secretary-General of the OECD, in Berlin on 4-5 July 2016

    The Secretary-General attended the Petersberg Climate Dialogue VII and delivered remarks at the session on “Making finance flows consistent with a pathway towards low greenhouse gas emissions and climate-resilient development”.

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