Environment Directorate

The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins

In series:OECD Series on Testing and Assessmentview more titles

Published on September 03, 2014

This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to those key events. AOPs can be incorporated into chemical categories-based assessments or integrated approaches for testing and assessment.