Is there life on Mars? -article by Julia Laplane, OECD
English, PDF, 1,466kb
Sustainable Materials Management (SMM) is increasingly recognised as a policy approach that can make a key contribution to green growth and the challenges that are posed by sustained global economic and demogarphic growth.
English, PDF, 1,424kb
This report focuses on four key policy issues: life-cycle externalities, trade policy impacts, material substitution and hazardous waste policies, and used and end-of-life mobile device management. Across these key policy issues, this report has identified the following observations relating to sustainable materials management.
The eleventh meeting of the Convention on Biological Diversity was held in Hyderabad, India (COP11, from 8 to 19 October 2012).
It is increasingly common to include estimates of value of statistical life (VSL) in analyses of proposed policies that affect people’s mortality risks.
The new Test Guidelines are: TG 457 and TG 460. The updated Test Guidelines are TG 109, TG 114, TG 229, TG 211, TG 305, TG 455, and TG 405. The corrected Test Guideline is TG 443
Developing effective policies to reduce illegal trade in environmentally sensitive goods requires a clear understanding of what drives this trade and the circumstances under which it thrives, says this report.
English, PDF, 1,097kb
This brochure (version: October 2012) presents the activities of the OECD "Working Group on Harmonisation of Regulatory Oversight in Biotechnology" and the "Task Force for the Safety of Novel Foods and Feeds”.
This Test Guideline describes an in vitro assay, which provides concentration-response data for substances with in vitro ER agonist and antagonist activity. The test system utilises the BG1Luc4E2 cell line derived from a human ovarian adenocarcinoma and stably transfected with a ER responsive luciferase reporter gene. This cell line can evaluate TA mediated by ER alpha and ER beta. The cells are plated into 96-well plate and exposed to 7 (range finder tests) and 11 (comprehensive test) non-cytotoxic concentrations of the test chemical for 19-24 hours to induce the reporter gene product (luciferase). Its activity is measured in a luminometer. Acceptance or rejection of a test is based on the evaluation of reference standard and control results from each experiment conducted on a 96-well plate. A positive response is identified by a concentration–response curve containing at least three points with non-overlapping error bars, as well as a change in amplitude (normalized relative light unit) of at least 20 % of the maximal value for the reference substance (17beta-estradiol for the agonist assay, raloxifene HCL/ 17beta-estradiol for the antagonist assay).