Latest Documents


  • 3-September-2014

    English

    The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins

    This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to those key events. AOPs can be incorporated into chemical categories-based assessments or integrated approaches for testing and assessment.
     

  • 3-September-2014

    English

    Guidance Document on the Honey Bee (Apis Mellifera L.) Brood test Under Semi-field Conditions

    The method described in this guidance document assesses the effects of plant protection products (PPPs), and has been validated using the active Fenoxycarb, which is known to act as an insect growth regulator (IGR), to the honey bee brood (Apis mellifera L.) under semi-field conditions (tunnel conditions followed by field conditions). The method can be used to address concerns regarding the impact on the brood development in honey bee colonies which are exposed to treatments of PPPs in agricultural crops. The aim of this test is to fill an identified gap or complement the sequential testing scheme with the development of a test method under semi-field conditions and to produce quantitative data that can be used as the basis for the evaluation of IGRs and other larvicidal compounds.

  • 3-September-2014

    English

    Guidance Document on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption

    This document is a tool to support regulatory authorities’ decisions on the hazard of specific chemicals when they receive test results from a Test Guideline (TG) or draft TG for the screening/testing of chemicals for endocrine disrupting properties. The contexts for these decisions will vary, depending on local legislation and practice, so the advice is worded in such a way as to permit flexible interpretation. It provides guidance on how to interpret the outcome of individual tests and how to increase evidence on whether or not a substance may be an endocrine disrupter; to this end, it recommends a test method that may be performed if regulatory authorities need more evidence.

  • 3-September-2014

    English

    Detailed Review Paper (DRP) on Molluscs Life-cycle Toxicity Testing

    This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals, and if so, to recommend suitable methods for optimisation and validation.

  • 3-September-2014

    English

    OECD Guidance on Pesticide Compliance and Enforcement Best Practices

    This Best Practices Guidance addresses compliance and enforcement issues as they relate to pesticides and associated health and environmental risks. The objective of this document is to provide guidance for promoting and monitoring compliance and for assessing and mitigating risks of non-compliance. It is targeted primarily at pesticide regulators, but may also interest policy makers as well as regulated parties (i.e. pesticide industry). This document addresses the following areas of the pesticide life-cycle: manufacturing and product integrity; distribution (including transportation and sale); product use; product storage; and container recycling and disposal.

  • 3-September-2014

    English

    Guidance on Developing Safety Performance Indicators For Public Authorities and Communities/Public

    This Document was designed to serve as a tool to assist industrial enterprises, public authorities, and communities near hazardous installations world-wide develop and implement a means to assess the success of their chemical safety activities. The guidance does not define a precise methodology, but rather provides guidance on how to develop and use safety performance indicators including the general elements of Safety Performance Indicators (SPI) Programmes.
     

  • 3-September-2014

    English

    OECD Issue Paper on Microbial Contaminants Limits for Microbial Pest Control Products

    This document examines the establishment of acceptable limits of microbiological contamination in microbial pest control products.

  • 3-September-2014

    English

    Water Treatment Chemicals

    This OECD Emission Scenario Document (ESD)  provides information on the
    sources, use patterns and release pathways of chemicals used in the treatment of water in a number of areas to assist in the estimation of releases of chemicals to the environment.
     

  • 3-September-2014

    English

    Formulation of Radiation Curable Coatings, Inks and Adhesives

    This OECD Emission Scenario Document (ESD) provides information on the sources, use patterns, and potential release pathways of chemicals used in the radiation curable products industry, specifically during formulation of radiation curable coatings, inks, and adhesives. The document focuses primarily on ultraviolet (UV) and electron beam (EB) curable products and presents standard approaches for estimating the environmental releases of and occupational exposures to components and additives used in radiation curable products.
     

  • 3-September-2014

    English

    Blending of Fragrance Oils into Commercial and Consumer Products

    The scope of this Emissions Scenario Document includes the blending of fine and functional fragrance oils into consumer and commercial products. The manufacture of aroma chemicals and the formulation of fragrance oil are outside the scope of this scenario. However, these industrial operations are discussed in this section as an introduction to the fragrance industry as a whole. The following life-cycle diagram demonstrates the applicability of this scenario.
     

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