Latest Documents


  • 3-September-2014

    English

    Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors

    This document describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations, such as obesity/diabetes/metabolic syndrome, reproductive dysfunction, and neuro-developmental abnormalities. Assays and endpoints are described that could be used in new or existing OECD Test Guidelines for evaluating chemicals for endocrine-disrupting activity. Endocrine pathways evaluated are the hypothalamus:pituitary:adrenocortical (HPA) axis, the hypothalamus:pituitary:gonad (HPG) axis, the somatotropic axis, the retinoid signaling pathway, the hypothalamus:pituitary:thyroid (HPT) axis, the vitamin D signaling pathway, and the peroxisome proliferator-activated receptor (PPAR) signaling pathway.

  • 3-September-2014

    English

    Insecticides, Acaricides and Products to Control Other Arthropods for Household and Professional Uses

    This Emission Scenario Document (ESD) is intended to provide information to be used for risk
    assessment for active substances and products used as biocidal (i.e. non agricultural) insecticides, acaricides and products to control other arthropods (in the EU, product type 18 [PT18] c).

  • 3-September-2014

    English

    Chemicals Used in Oil Well Production

    This OECD Emission Scenario Document (ESD) provides information on the sources, use patterns, and potential release pathways of chemicals used in petroleum production at oil wells. The document presents standard approaches for estimating the environmental releases of and occupational exposures to oil production chemicals.

  • 3-September-2014

    English

    Water Based Washing Operations at Industrial and Institutional Laundries

    This OECD Emission Scenario Document (ESD) is intended to provide information on the sources, use patterns, and potential release pathways of chemicals to be used in water washing machines at industrial and institutional laundries. The document presents standard approaches for estimating the environmental releases of and occupational exposures to chemicals used in water washing machines in laundries.

  • 3-September-2014

    English

    Radiation Curable Coating, Inks and Adhesives

    This OECD Emission Scenario Document (ESD) provides information on the sources, use patterns, and potential release pathways of chemicals used in the radiation curable products
    industry, specifically during application of radiation curable coatings, inks, and adhesives. The document focuses primarily on ultraviolet (UV) and electron beam (EB) curable products and presents standard approaches for estimating the environmental releases of and occupational exposures to components and additives used in radiation curable products.
     

  • 3-September-2014

    English

    Coating Industry (Paints, Lacquers and Varnishes)

    This OECD Emission Scenario Document (ESD) is intended to provide information on the
    sources, use patterns and release pathways of chemicals used in the coatings industry (paints,
    lacquers and varnishes), to assist in the estimation of releases of chemicals into the environment.
     

  • 3-September-2014

    English

    Report of the OECD Seminar on Risk Reduction through Prevention, Detection and Control of the Illegal International Trade in Agricultural Pesticides

    This document is the report of the OECD Seminar on Risk Reduction through Prevention, Detection and Control of the Illegal International Trade in Agricultural Pesticides that took place on 19 May, 2010 at OECD, Paris, France, and was chaired by Dr. Wolfgang Zornbach of the German Federal Ministry of Food, Agriculture and Consumer Protection. After a series of presentations on governments‟ and other stakeholders‟ approaches and experiences (copies of all presentations are in Annex 4), the Seminar discussed the various issues associated with the illegal international trade of pesticides: risks and consequences of using illegal pesticides, risks linked to the pesticide supply/logistical chain, existing systems in place in countries, difficulties faced by authorities and customs, etc. The Seminar developed a set of recommendations targeted at governments, industry, all stakeholders and OECD.
     

  • 3-September-2014

    English

    The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins

    This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to those key events. AOPs can be incorporated into chemical categories-based assessments or integrated approaches for testing and assessment.
     

  • 3-September-2014

    English

    Guidance Document on the Honey Bee (Apis Mellifera L.) Brood test Under Semi-field Conditions

    The method described in this guidance document assesses the effects of plant protection products (PPPs), and has been validated using the active Fenoxycarb, which is known to act as an insect growth regulator (IGR), to the honey bee brood (Apis mellifera L.) under semi-field conditions (tunnel conditions followed by field conditions). The method can be used to address concerns regarding the impact on the brood development in honey bee colonies which are exposed to treatments of PPPs in agricultural crops. The aim of this test is to fill an identified gap or complement the sequential testing scheme with the development of a test method under semi-field conditions and to produce quantitative data that can be used as the basis for the evaluation of IGRs and other larvicidal compounds.

  • 3-September-2014

    English

    Guidance Document on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption

    This document is a tool to support regulatory authorities’ decisions on the hazard of specific chemicals when they receive test results from a Test Guideline (TG) or draft TG for the screening/testing of chemicals for endocrine disrupting properties. The contexts for these decisions will vary, depending on local legislation and practice, so the advice is worded in such a way as to permit flexible interpretation. It provides guidance on how to interpret the outcome of individual tests and how to increase evidence on whether or not a substance may be an endocrine disrupter; to this end, it recommends a test method that may be performed if regulatory authorities need more evidence.

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