Latest Documents


  • 3-September-2014

    English

    Guidance Document on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption

    This document is a tool to support regulatory authorities’ decisions on the hazard of specific chemicals when they receive test results from a Test Guideline (TG) or draft TG for the screening/testing of chemicals for endocrine disrupting properties. The contexts for these decisions will vary, depending on local legislation and practice, so the advice is worded in such a way as to permit flexible interpretation. It provides guidance on how to interpret the outcome of individual tests and how to increase evidence on whether or not a substance may be an endocrine disrupter; to this end, it recommends a test method that may be performed if regulatory authorities need more evidence.

  • 3-September-2014

    English

    Detailed Review Paper (DRP) on Molluscs Life-cycle Toxicity Testing

    This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals, and if so, to recommend suitable methods for optimisation and validation.

  • 3-September-2014

    English

    The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals

    This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.
     

  • 3-September-2014

    English

    Current Approaches in the Statistical Analysis of Ecotoxicity Data - A guidance to application (annexes to this publication exist as a separate document)

    This document describes the main statistical methods used for analysis of data from ecotoxicological studies .

  • 3-September-2014

    English

    Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors

    Increasing incidents of disorders such as obesity/diabetes/metabolic syndrome, reproductive dysfunction, and neuro-developmental abnormalities in some human populations have raised concern that disruption of key endocrine-signaling pathways by exposure to environmental chemicals may be involved. This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.

  • 3-September-2014

    English

    Report of the OECD workshop on Integrated Pest Management (IPM) - Strategies for the adoption and Implementation of IPM in Agriculture Contributing to the Sustainable Use of Pesticides and to Pesticide Risk Reduction

    This document is the report of the “OECD Workshop on Integrated Pest Management (IPM) -
    Strategies for the adoption and implementation of IPM in agriculture contributing to the sustainable use of
    pesticides and to pesticide risk reduction”, that took place on 16 19 October 2011, in Berlin, Germany, and
    was chaired by Dr. Wolfgang Zornbach of the German Federal Ministry of Food, Agriculture and
    Consumer Protection.

    The developed detailed recommendations for promoting and facilitating the adoption and implementation of IPM strategies and for encouraging appropriate stakeholders to use IPM tools and measures. The workshop was planned in the framework of the “OECD Strategic Approach in Pesticide Risk Reduction”. It addressed the following four main issues: technology and Information, economics and market access, policies and strategies and measurements and impact.  This report includes the outcomes of the workshop discussions, as well as the overall workshop conclusions (Section 4) and recommendations (Section 5) targeted at governments, all stakeholders and OECD.
     

  • 3-September-2014

    English

    Fish Toxicity Testing Framework

    This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant. A review of regulatory needs for fish tests under various jurisdictions in OECD countries is provided in Chapter 2, followed by a review of statistical issues and general test considerations in Chapters 3 and 4, respectively. The document examines animal welfare concerns and alternatives to fish tests in Chapter 5. Chapter 6 provides a systematic review of existing and draft OECD Guidelines which use fish for toxicity or bioaccumulation studies. Finally Chapter 7 describes a generic framework for assessing the environmental hazards of chemicals using fish tests in the most efficient way. An Annex contains conclusions and recommendations made and agreed at the workshop in September 2010. The recommendations concern, among other aspects, possible improvements to existing Test Guidelines, development of guidance on specific issues, harmonisation of existing Test Guidelines for common issues, development of new Test Guidelines, and proposals for deletion of outdated Test Guidelines.
     

  • 2-September-2014

    English

    Transport and Storage of Chemicals

    This OECD Emission Scenario Document (ESD) provides information on the sources and release pathways of chemicals during their transport and storage in a wide range of industries, to help estimate releases of chemicals into the environment. This ESD covers the transport and storage of chemicals either as pure chemicals or as components of finished products. However, it does not consider the following: mixed waste streams, radioactive substances, biological and infectious materials and foodstuffs.
     

  • 2-September-2014

    English

    Insecticides, Acaricides and Products to Control Other Arthropods for Household and Professional Uses

    This Emission Scenario Document (ESD) is intended to provide information to be used for risk
    assessment for active substances and products used as biocidal (i.e. non agricultural) insecticides, acaricides and products to control other arthropods (in the EU, product type 18 [PT18] c).

  • 2-September-2014

    English

    Chemicals Used in Oil Well Production

    This OECD Emission Scenario Document (ESD) provides information on the sources, use patterns, and potential release pathways of chemicals used in petroleum production at oil wells. The document presents standard approaches for estimating the environmental releases of and occupational exposures to oil production chemicals.

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