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This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals, and if so, to recommend suitable methods for optimisation and validation.
This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.
This document describes the main statistical methods used for analysis of data from ecotoxicological studies .
Increasing incidents of disorders such as obesity/diabetes/metabolic syndrome, reproductive dysfunction, and neuro-developmental abnormalities in some human populations have raised concern that disruption of key endocrine-signaling pathways by exposure to environmental chemicals may be involved. This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption
This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant. A review of regulatory needs for fish tests under various jurisdictions in OECD countries is provided in Chapter 2, followed by a review of statistical issues and general test considerations in Chapters 3 and 4, respectively. The
This OECD Emission Scenario Document (ESD) provides information on the sources and release pathways of chemicals during their transport and storage in a wide range of industries, to help estimate releases of chemicals into the environment. This ESD covers the transport and storage of chemicals either as pure chemicals or as components of finished products. However, it does not consider the following: mixed waste streams,
This Emission Scenario Document (ESD) is intended to provide information to be used for risk
assessment for active substances and products used as biocidal (i.e. non agricultural) insecticides, acaricides and products to control other arthropods (in the EU, product type 18 [PT18] c).
This OECD Emission Scenario Document (ESD) provides information on the sources, use patterns, and potential release pathways of chemicals used in petroleum production at oil wells. The document presents standard approaches for estimating the environmental releases of and occupational exposures to oil production chemicals.
This OECD Emission Scenario Document (ESD) is intended to provide information on the sources, use patterns, and potential release pathways of chemicals to be used in water washing machines at industrial and institutional laundries. The document presents standard approaches for estimating the environmental releases of and occupational exposures to chemicals used in water washing machines in laundries.
This OECD Emission Scenario Document (ESD) provides information on the sources, use patterns, and potential release pathways of chemicals used in the radiation curable products
industry, specifically during application of radiation curable coatings, inks, and adhesives. The document focuses primarily on ultraviolet (UV) and electron beam (EB) curable products and presents standard approaches for estimating the environmental