Testing of chemicals

Toxicogenomics

 

Current OECD activities


(1) Molecular Screening Project
The current OECD work in this field focuses on the Molecular Screening Project started in 2007 and led by the US. For the details of this project, see here.
 
(2) Survey on the Available Omics Tools
In the preparation for the OECD/IPCS Workshop on Toxicogenomics in Kyoto in November 2004 (see below), the OECD Secretariat conducted a survey on existing toxicogenomic tools in OECD member countries.

Since the survey, there has been accelerating development in the toxicogenomic field. In view of this situation, the OECD/IPCS Advisory Group on Toxicogenomics agreed to follow-up current approaches in toxicogenomics in member countries. The result of the follow-up survey led by Japan was published in January 2009.

 


OECD/IPCS Workshops


The work initially started in close cooperation with the International Programme on Chemical Safety (IPCS) on Toxicogenomics. In order to develop a strategy concerning the future application of toxicogenomics in regulatory assessment of chemical safety, the OECD, along with the IPCS, organized twin workshops.
The first workshop on human health aspects was held in November 2003 in Berlin, with the IPCS in the lead. The OECD took a lead of the second workshop held in October 2004 in Kyoto, Japan which focuses on eco-toxicological aspects.

 


Member Countries’ Activities on Toxicogenomics


For the future application of toxicogenomics and Molecular Screening Technologies in regulatory assessment of chemical safety, various novel efforts are implemented or planned among member countries.
For instance, the U.S. Environmental Protection Agency (EPA) published the white paper titled “Potential Implications of Genomics for Regulatory and Risk Assessment Applications at EPA” in December 2004. This paper was issued to present exemplary applications and resultant implications of the use of genomics technologies in EPA practice.

 

 

 

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