Testing of chemicals

Acute Toxicity

 

Acute Oral Toxicity

TG 420: Acute Oral Toxicity - Fixed Dose Procedure
TG 423: Acute Oral toxicity - Acute Toxic Class Method
TG 425: Acute Oral Toxicity: Up-and-Down Procedure



General documents:

•    No 24: Guidance Document on Acute Oral Toxicity Testing
•    No 129: Guidance Document on Using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systematic Toxicity TestsNo
•    No 124: Guidance for the Derivation of an Acute Reference Dose

 

Acute Dermal Toxicity

TG 402: Acute Dermal Toxicity

 

Acute Inhalation Toxicity

TG 403: Acute Inhalation Toxicity
TG 436: Acute Inhalation Toxicity – Acute Toxic Class Method
•    No 104: Performance Assessment: Comparison of 403 and CXT Protocols via Simulation and for Selected Real Data Sets
•    No 105: Report on Biostatistical Performance Assessment of the Draft TG 436 Acute Toxic Class Testing Method
                     for Acute Inhalation Toxicity

 

General documents:

•    No 39: Guidance Document on Acute Inhalation Toxicity Testing
•    No 153: Guidance Document for the Derivation of an Acute Reference Concentration (Arfc)

 

 

 

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