Testing of chemicals

OECD Guidelines for the Testing of Chemicals


The OECD Guidelines are a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as standard methods for safety testing, the Guidelines are used by professionals in industry, academia and government involved in the testing and assessment of chemicals (industrial chemicals, pesticides, personal care products, etc.). These Guidelines are regularly updated with the assistance of thousands of national experts from OECD member countries. OECD Test Guidelines are covered by the Mutual Acceptance of Data, implying that data generated in the testing of chemicals in an OECD member country, or a partner country having adhered to the Decision, in accordance with OECD Test Guidelines and Principles of Good Laboratory Practice (GLP), be accepted in other OECD countries and partner counties having adhered to the Decision, for the purposes of assessment and other uses relating to the protection of human health and the environment.


*In 2017, the section 3 “Degradation and Accumulation” was renamed to “ Environmental Fate and Behaviour”  to take into account Test Guidelines measuring endpoints such as dispersion, aggregation.

Related Documents


Test Guidelines that have been deleted or replaced by updated versions

These obsolete Test Guidelines have been deleted in order to allow national/regional regulations that make reference to specific Test Guidelines and versions to be updated accordingly.  They should not be used for new testing. They are included here because it may be useful to consult them in the framework of the assessment of substances based on old study reports. The guaranties of Mutual Acceptance of Data (MAD) would not apply if these Test Guidelines were used for new testing.

In November 2012, the Joint Meeting of the Chemicals Committee and Working Party on Chemicals, Pesticides and Biotechnology decided on a transition period of 18 months, between the Council Decision and the effective deletion, for Test Guidelines that have been updated or deleted. For more information, please read the presentation: Update of Test Guidelines and the Mutual Acceptance of Data.

Further reading


Related Documents