Testing of chemicals

Level 3: In vivo Assays Providing Data About Selected Endocrine Mechanism(s)/Pathway(s)

 

Amphibian Metamorphosis Assay

TG 231: Amphibian Metamorphosis Assay

•    No 46: Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances
•    No 76: Final Report of the Validation of the Amphibian Metamorphosis Assay for the Detection of Thyroid Active
                  Substances - Phase 1: Optimisation of the Test Protocol
•    No 77: Final Report of the Validation of the Amphibian Metamorphosis Assay - Phase 2: Multi-chemical Interlaboratory Study
•    No 82: Guidance Document on Amphibian Histology
•    No 91: Report of the Validation of the Amphibian Metamorphosis Assay (Phase 3)
•    No 92: Report of the Validation Peer Review for the Amphibian Metamophosis Assay and Agreement of the Working Group of the
                  National Coordinators of the Test Guidelines Programme on the Follow-up of this Report



Fish Reproductive Screening Assay

TG 229: Fish Short Term Reproduction Assay



Fish Screening Assay

TG 230: 21-day Fish Assay

•    No 60: Report of the Initial Work Towards the Validation of the 21-day Fish Screening Assay for the Detection of Endocrine Active
                  Substances - Phase 1A
•    No 61: Report of the Validation of the 21-day Fish Screening Assay for the Detection of Endocrine Active Substances - Phase 1B
•    No 78: Final Report of the Validation of the 21-day Fish Screening Assay for the Detection of Endocrine Active
                  Substances - Phase 2: Testing Negative Substances
•    No 94: Report of the Validation Peer Review for the 21-day Fish Endocrine Screening Assay and Agreement of the Working Group
                   of the National Coordinators of the Test Guidelines Programme on the Follow-up of the Report
•    No 109: Literature Review on the 21-day Fish Assay and the Fish Short-term Reproduction Assay
•    No 127:  Peer Review Report of the Validation of the 21-day Androgenised Female Stickleback Screening Assay
•    No 128: Validation Report on the 21-day Androgenised Female Stickleback Screening Assay




 

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