Draft Guidance Document on the Bhas 42 Cell Transformation Assay (CTA): deadline for public comment set for 25 September 2015.
A new publication is available in this series: Report on the Workshop on a Framework for the Development and use of Integrated Approaches to Testing and Assessment (No. 215).
This is the OECD Good Laboratory Practice homepage. The primary objective of the OECD Principles of GLP is to ensure the generation of high quality and reliable test data related to the safety of industrial chemical substances.
The OECD Guidelines for the Testing of Chemicals are a collection of the most relevant internationally agreed test methods used by government, industry and independent laboratories to determine the safety of chemicals and chemical preparations, including pesticides and industrial chemicals.
English, PDF, 771kb
This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test.
English, PDF, 184kb
This Test Guideline is designed for assessing the effects of chemicals on the reproductive output of the collembolans in soil. It is based on existing procedures (1) (2). The parthenogenetic Folsomia candida and sexually reproducing Folsomia fimetaria are two of the most accessible species of Collembola, and they are culturable and commercially available.
An IT system to develop and evaluate Adverse Outcome Pathways (AOP), the AOP Wiki, has been developed for testing by the Extended Advisory Group on Molecular Screening and Toxicogenomics and by AOP developers included in the work plan. The Wiki provides developers the necessary steps to capture scientific information in a user-friendly manner. The project is jointly led by the ECJRC and the USEPA.
In 2011, Brazil joined OECD’s Mutual Acceptance of Data (MAD) system ensuring that its chemical safety test data will be accepted by all 40 countries adhering to MAD. Originally limited to data developed in Brazil on pesticides, biocides and industrial chemicals, it now also includes veterinary products, feed additives, cosmetics, pharmaceutical products, sanitizers, wood preservative and treatments of effluents and natural ecosystems.
The OECD has just published two new Test Guidelines on human health hazard endpoint skin sensitisation. Skin sensitisation refers to an allergic response following skin contact with the tested chemical, as defined by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS).
This page explains the background to the OECD Test Guidelines, the reason for their development, their applicability and how they can be accessed.