Testing of chemicals

Draft Guidance and Review Documents/Monographs


The OECD Guidelines for the Testing of Chemicals are a unique tool for assessing the potential effects of chemicals on human health and the environment.

The Guidelines are regularly updated with the assistance of thousands of national experts from OECD member countries; and are covered by the Mutual Acceptance of Data, implying that data generated in the testing of chemicals in an OECD member country, or a partner country having adhered to the Decision, in accordance with OECD Test Guidelines and Principles of Good Laboratory Practice (GLP), be accepted in other OECD countries and partner counties having adhered to the Decision.

current deadlines for comments

30 OCTOBER 2018

12 MARCH 2018

31 MARCH 2018 

  1. Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits. 

  2. Chronic binding of antagonist to N-methyl-D-aspartate receptors (NMDARs) during brain development leads to neurodegeneration with impairment in learning and memory in aging.

  3. Androgen receptor agonism leading to reproductive dysfunction

28 FEBRUARY 2018

 12 FEBRUARY 2018




* Comments should be sent to the Secretariat by National co-ordinators. To contribute to a commenting round, you are invited to contact your National co-ordinator beforehand and discuss together a timeframe for comment submission.



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