Testing of chemicals

Carcinogenicity

 

TG 451: Carcinogenicity studies (2009)


TG 453: Combined chronic toxicity/carcinogenicity studies (2009)
•    No 35: Guidance notes for analysis and evaluation of chronic toxicity and carcinogenicity studies
•    No 116: Guidance document on the conduct and design of chronic toxicity and carcinogenicity studies, supporting
                     test guidelines 451, 452, and 453 - second edition (2011)


No 208
: BHAS 42 cell transformation assay validation study report


Cell transformation assays
No 31: Detailed review paper on cell transformation assays for detection of chemical carcinogens
No 146: Syrian Hamster Embryonic (SHE) cell PH 6.7 cell transformation assay prevalidation study report (2011)
No 147: Syrian Hamster Embryonic (SHE) cell PH 7.0 cell transformation assay prevalidation study report (2011)
No 149: Validation report of the Balb/c 3T3 cell transformation assay (2011)
No 163:  Peer review report related to three cell transformation assays and agreement of the Working Group of the National
                Coordinators of the Test Guidelines Programme on the follow-up to the peer review

 

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