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  • 4-May-2018

    English

    Memorandum of Understanding between the OECD and the Guangdong Provincial Centre for Disease Control and Prevention

    The OECD welcomed a Memorandum of Understanding (MOU) between the Guangdong Provincial Centre for Disease Control and Prevention and the OECD which will support China’s efforts in chemicals regulation and policy making.

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  • 12-April-2018

    English

    Publications in the series on Pollutant Release and Transfer Registers

    This new council act recommends that Member countries take steps to establish, as appropriate, implement and make publicly available a pollutant release and transfer register (PRTR) system using the principles and information set forth in the OECD Guidance Documents on PRTRs.

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  • 9-April-2018

    English

    Intellectual Property elements in OECD Test Guidelines

    Ten years ago, OECD started to develop tools to avoid market monopoly as far as possible, to avoid abusive situations and to maintain transparency in OECD Test Guidelines containing Intellectual Property (IP) elements. Find out how the OECD address protected elements in OECD Test Guidelines.

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  • 22-March-2018

    English

    Economic assessment and valuations of environmental and health impacts caused by Perfluorooctanoic acid (PFOA) and its salts - Environment Working Paper

    Perfluorooctanoic acid (PFOA) is being used in fluoropolymer production, as surface treatment agents and for the manufacture of side-chain fluorinated polymers. However, there is evidence that PFOA and its salts have a number of hazardous properties that may cause harm to human health and the environment. This report evaluates existing economic assessments and valuations of impacts arising from PFOA and its salts.

  • 23-February-2018

    English

    OECD Good Laboratory Practice: Frequently asked questions (FAQ)

    GLP issues raised by testing labs are covered in this comprehensive list of questions and answers, recently updated with questions related to: sponsors, Contract Research Organisations (CROs), sub-contractors, archives, Information Technology (IT), Biotechnology/GMOs and other miscellaneous issues

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  • 3-January-2018

    English

    Exposure Assessment

    Risks to human health and the environment posed by chemicals is determined by the chemical-specific hazard properties and the extent of exposure to chemicals. Read more on the OECD work in developing and harmonising methods for assessing the exposure of chemicals to humans and the environment.

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  • 21-December-2017

    English

    Safety Assessment of Transgenic Organisms in the Environment, Volume 7 - OECD Consensus Documents

    Volume 7 of the Series compiles the OECD consensus documents for use in environmental risk assessment of transgenic organisms (biosafety) issued in 2016 and 2017.The first two chapters cover the biology of plant species (sorghum and tomato) and include elements of taxonomy, centres of origin, reproductive biology, genetics, outcrossing, crop production and cultivation practices, interactions with other organisms, main pests and pathogens, and biotechnological developments.The third chapter relates to Atlantic salmon, the first OECD biosafety publication to address an animal species. It describes the biology and ecology of wild salmon (including classification, life stages, reproduction, centres of origin, geographical distribution, population dynamics, interaction with other organisms) and of the farmed form (domestication, aquaculture rearing practices, biocontainment, interactions with the external environment). It also provides elements of genetics, research on genetically engineered salmon and resources for its risk assessment.
  • 6-December-2017

    English

    BioTrack Product Database

    This OECD database allows regulatory officials and stakeholders to share information on products derived from the use of modern biotechnology, as well as some products with novel traits acquired by the use of conventional breeding or mutagenesis, that have been approved for commercial application in at least one country, in terms of food, feed or environmental safety.

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  • 4-December-2017

    English

    Environmental biosafety

    Most OECD countries and many non-members have a system of regulatory oversight for products of modern biotechnology (genetically-engineered /transgenic organisms) which are intended for release to the environment. The OECD biosafety work programme aims to consider all types of organisms (plants, trees, animals, micro-organisms) and to promote international harmonisation.

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  • 9-October-2017

    English

    Test No. 405: Acute Eye Irritation/Corrosion

    This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is applied in a single dose in the conjunctival sac of one eye of each animal. The other eye, which remains untreated, serves as a control. The initial test uses an animal; the dose level depends on the test substance nature. A confirmatory test should be made if a corrosive effect is not observed in the initial test, the irritant or negative response should be confirmed using up to two additional animals. It is recommended that it be conducted in a sequential manner in one animal at a time, rather than exposing the two additional animals simultaneously. The duration of the observation period should be sufficient to evaluate fully the magnitude and reversibility of the effects observed. The eyes should be examined at 1, 24, 48, and 72 hours after test substance application. The ocular irritation scores should be evaluated in conjunction with the nature and severity of lesions, and their reversibility or lack of reversibility. Use of topical anesthetics and systemic analgesics to avoid or minimize pain and distress in ocular safety testing procedures is described.
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