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The Pesticides Programme has undertaken work to: (i) identify and overcome obstacles to work-sharing; (ii) harmonise data requirements and test guidelines; and (iii) harmonise hazard/risk assessment approaches.
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This guidance document focuses on microbiological efficacy testing. It covers efficacy testing of articles treated with antimicrobials in the manufacturing process with the intention of the achieving an external effect.
This Test Guideline describes a method to estimate the developmental toxicity of a test chemical to the dung dwelling life stages of dung-dependent dipteran species. Two test species can be used. The test chemical is mixed with bovine faeces, to which either 10 eggs of Scathophaga stercoraria or 10 larvae of Musca autumnalis are added. The test will be terminated 5 days after emergence of the last adult in the control (> 18 days for S. stercoraria, >13 days for M. autumnalis). Then the possible impacts of the test chemical on the following measurement endpoints are assessed under controlled conditions: sex and total number of emerged adult flies, retardation of emergence indicated by the developmental rate and morphological change. Depending on the experimental design, the No Observed Effect Concentration (NOEC) or the Effect concentration for x percent effect (ECx) can be determined. This Guideline can be used for water soluble or insoluble substances, but is not applicable to volatile substances. If the toxicity of the chemical is unknown, five nominal test concentrations should be conducted. A positive control should be tested periodically. The test is considered valid if in the controls hatching of larvae is superior or equal to 70% of the number of introduced eggs, emergence of adults is superior or equal to 70% and superior or equal to 50% of the respectively hatched and introduced larvae and if the emergence of adult flies starts after 18 +- 2 days (S. stercoraria) or after 13 +- 2 days(M. autumnalis).
This Test Guideline describes a method to assess the effects of chemical substances in soil on the reproductive output of the soil mite species Hypoaspis (Geolaelaps) aculeifer Canestrini (Acari: Laelapidae). It can be used for water soluble or insoluble substances, but not with volatile substances.
Adult females of similar age are exposed to a range of concentrations of the test substance mixed into 20 g dry mass of artificial soil 28-35 days after the start of the egg laying period. Depending on the endpoint (ECx, NOEC or both), five to twelve concentrations should be tested. At least two to four replicates for each test concentrations and six to eight control replicates, of 10 animals each, are recommended. At 20¡ãC, the test lasts 14 days after introducing the females, which usually allows the control offspring to reach the deutonymph stage. The number of surviving females (mortality ¡Ü 20% for a valid test) and the number of juveniles per test vessel (at least 50 for a valid test) are determined. The fecundity of the mites exposed to the test substance is compared to that of controls in order to determine the ECx (e.g. EC10, EC50) or the No Observed Effect Concentration (NOEC). Any observed differences between the behaviour and the morphology of the mites in the control and the treated vessels should be recorded.
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The report is a collation of various aspects such as responsible regulatory authorities/agencies, data requirements, activities being pursued and regulatory mechanisms for approving minor uses in member countries.
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This report presents the results of an OECD seminar on ways to achieve risk reduction while addressing issues associated with the use of chemical pesticides or non-chemical means of crop protection on a small scale.
This document intends to provide a “snapshot” of how OECD countries have developed and run their PRTR programmes. It shows the similarities and differences across countries in their requirements to collect and display high quality data, which is required for an effective PRTR system. It also presents compliance and regulatory requirements, the development of guidance material, and emerging issues and challenges for the future.
This page lists, in chronological order, the Pesticides Publication Series that relate to Minor Uses.
OECD’s Working Party on Manufactured Nanomaterials launched a “sponsorship programme” at its 3rd meeting (November 2007). Countries will share the testing of specific nanomaterials (MNs) under this programme.
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This report presents the results of an OECD seminar on ways to achieve pesticide risk reduction through worker safety and training. The seminar was hosted by Czech State Phytosanitary Administration, in Brno, Czech Republic, on 21 March 2007.