The OECD Guidelines are a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as standard methods for safety testing, the Guidelines are used by professionals in industry, academia and government involved in the testing and assessment of chemicals. These Guidelines are regularly updated with the assistance of thousands of national experts from OECD member countries.
This report aims to enhance awareness for inclusion of children’s exposure in risk assessments when relevant and presents a children’s exposure decision tree that facilitates such decisions. The decision tree can be used to identify if a separate exposure assessment is needed with regard to children, and also aims to identify whether the exposure assessment conducted for adults already provides an acceptable level of safety of children.
Two new cases have been published that focus on use of metabolism information to support read-across and use of a combination of novel methods to identify potential endocrine disruptors, respectively. In addition a considerations document includes lessons and learnings from analysis across case studies and an analysis of uncertainties in six read-across cases.
The purpose of this document is to give guidance to Receiving Authorities on the evaluation of the GLP compliance status of nonclinical safety studies submitted for regulatory purposes. This guidance does not address the scientific evaluation and interpretation of the submitted data or the risk assessment based on these data.
Policy instruments can be applied to improve the sustainability of plastics, including regulations, market-based instruments, information and voluntary tools. The report reviews the use of these instruments, provides good practice examples, such as product taxes and charges, eco-design standards, extended producer responsibility and environmental product labels, as well as discussing opportunities for their future applications.
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This new edition of the OECD work on Chemical Safety and Biosafety highlights the activities, results and ongoing projects as outlined by the 2019-2020 work programme.
GHSTS is a standardised set of technical specifications for assembling electronic files for pesticide registration in a predefined manner. Once assembled according to the GHSTS, the dossier files can be transferred from a business to a regulatory authority and can be used in a regulatory process. Version 2.0 includes improved lifecycle management of documents over a series of submissions for one pesticide (or other) regulatory action.
On 15 May 2019, Eeva Leinala of the OECD Environment Directorate, Sandi Moser of the Environment and Climate Change Canada, and Hannah Holsinger of the EPA presented the latest Risk Reduction Initiatives for Per- and Polyfluoroalkyl substances undertaken by Canada and the United States.
This page contains a list of the Guidelines for the Testing of Chemicals.
10-12 April 2019: The conference on RNA interference (RNAi) based pesticides will provide an overview of the current state of the knowledge of RNA interference (RNAi) as it relates to the potential use of this naturally occurring mode of action in agriculture. This will be an efficient route to this information for policy makers, particularly given the large volume of scientific information that is available in the literature.