Latest Documents

Substitution of hazardous chemicals

As interest in the substitution of harmful chemicals continues to grow in industry, NGOs and the public sector, organisations are seeking guidance on the selection of appropriate methods and tools. OECD is responding to this need.

More about OECD Test Guidelines

This page explains the background to the OECD Test Guidelines, the reason for their development, their applicability and how they can be accessed.

Guiding Principles for Chemical Accident Prevention, Preparedness and Response

The objective of these Guiding Principles is to set out general guidance for the safe planning, construction, management, operation and review of safety performance of hazardous installation in order to prevent accidents involving hazardous substances and, recognising that such accidents may nonetheless occur, to mitigate adverse effects through effective land-use planning and emergency preparedness and response.

Related Documents

• OECD-Leitprinzipien für die Verhinderung, Bereitschaft für den Fall und Bekämpfung von Chemieunfällen
• Hungarian Translation of the OECD Guiding Principles for Chemical Accident Prevention, Preparedness and Response
• Korean Translation of the OECD Guiding Principles for Chemical Accident Prevention, Preparedness and Response
• Principes directeurs de l'OCDE pour la prévention, la préparation et l' intervention en matière d'accidents chimiques
• Czech Translation of the Guiding Principles for Chemical Accident Prevention, Preparedness and Response
• Principi Guida dell’OCSE per la prevenzione, la preparazione e l’intervento nei casi di incidente chimico
• Chinese Translation of the Guiding Principles for Chemical Accident Prevention, Preparedness and Response

OECD biotechnology newsletter updates

OECD major events and activities relating to biotechnologies: latest developments are updated biannually in this Newsletter.

Guidance Document for Describing Non-Guideline In Vitro Test Methods

This guidance is intended to harmonise the way non-guideline in vitro test methods are described. This should in future facilitate an assessment of the relevance of test methods for biological activities and responses of interest, of the quality of data produced, irrespective of whether these tests are based on manual protocols or assay protocols adapted for use on automated platforms or high-throughput screening systems (HTS).

Children’s Health

Children can be more vulnerable than adults to chemicals. Considering global concern for children’s health, the OECD has been working to bring together knowledge and experiences to reduce risks to children’s health from chemicals.

Client-Server Configuration Manual: QSAR Toolbox Version 3.3

QSAR Toolbox

Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

An IT system to develop and evaluate Adverse Outcome Pathways (AOP), the AOP Wiki, has been developed for testing by the Extended Advisory Group on Molecular Screening and Toxicogenomics and by AOP developers included in the work plan. The Wiki provides developers the necessary steps to capture scientific information in a user-friendly manner. The project is jointly led by the ECJRC and the USEPA.

Genotoxicity of Manufactured Nanomaterials : Report of the OECD expert meeting

This report includes the conclusions and recommendations of an expert workshop on the genotoxicity of nanomaterials, which was organized by OECD’s Working Party on Manufactured Nanomaterials. The main topic was the applicability of existing OECD Test Guidelines (TG) for chemical safety to nanomaterials.

Guidance document on elements of a Pollutant Release and Transfer Registers (PRTR): Part 1

OECD countries have developed PRTR system to track releases and transfers of potentially harmful chemicals. To improve PRTR system, OECD have analysed common elements (pollutants, sectors) in different PRTR systems, mainly focus on institutional arrangement. This serves as a common framework for different PRTR system, and supporting materials for a country that intends to develop or update its PRTR.