Latest Documents

Substitution of hazardous chemicals

The first report is a synthesis from a Workshop on Approaches to Support Substitution and Alternatives Assessment, which discussed approaches used to support alternative assessments and substitution. The second report is a Cross Country Analysis of Approaches to Support Alternatives Assessment and Substitution of Chemicals of Concern that describes a list of approaches developed across countries and by different stakeholders.

OECD Test Guidelines for the Chemicals

The OECD Guidelines are a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as standard methods for safety testing, the Guidelines are used by professionals in industry, academia and government involved in the testing and assessment of chemicals. These Guidelines are regularly updated with the assistance of thousands of national experts from OECD member countries.

Pesticides publications (Chronological order)

Two new reports have been released in the Series on Pesticides: A Guidance Document for the Assessment of the Equivalence of Technical Grade Active Ingredients for Identical Microbial Strains and a Guidance Document on Residues in Rotational Crops.

Join our Webinar on Tuesday 29 January 2019 @ 4 pm (Paris time) / 10 am (EST time) on Environmental Best Practices for Class B Firefighting Foams

After an introduction by Eeva Leinala (OECD), Thomas Cortina from the Fire Fighting Foam Coalition and Mitch Hubert from Perimeter Solutions will address Best Environmental Practices for Class B Firefighting Foams in the context of management of per- and polyfluoroalkyl Substances (PFASs).

Saving Costs in Chemicals Management - How the OECD Ensures Benefits to Society

Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

The first report describes the linkage between inhibition of complex I of the mitochondrial respiratory chain and motor deficit as in parkinsonian disorders. The second report links chronic binding of antagonist to N-methyl-D-aspartate receptors during brain development leading to neurodegeneration. The third report details the linkage between binding and activation of androgen receptor leading to reproductive dysfunction.

“What will a changing ocean mean to us, our jobs and markets?”

The iconic ocean explorer Jacques Cousteau once said “For most of history, man has had to fight nature to survive; in this century he is beginning to realise that, in order to survive, he must protect it.”

Draft documents for public comments

This page contains a list of the Guidelines for the Testing of Chemicals.

Webinar Series on Testing and Assessment Methodologies

On 16 January 2019, Patience Browne of the Environment Directorate presented an overview of an on-going project led by the European Commission Joint Research Centre/the United States/ Health Canada.

Section 4: Health Effects

Consult the January and February 2019 deadlines for comment of various OECD Guidelines for the Testing of Chemicals: in Vitro 3T3 NRU phototoxicity test; Vitrigel Eye Irritancy Test Method; in vitro Macromolecular Test Method for Eye Hazard Potential; and In Chemico Skin Sensitisation Assays addressing the AOP Key Event of covalent binding to proteins.