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Micro-organisms play a fundamental role in the environment. Yet their role is the result of complex biogeochemical processes by consortia of micro-organisms and the function of individual species is not clear in many cases.
This publication provides an overview of the current situation and relevant developments in environmental microbiology, as well as its potential application, which covers: use of micro-organisms for
OECD major events and activities relating to biotechnologies: latest developments are updated biannually in this Newsletter.
This guidance is intended to harmonise the way non-guideline in vitro test methods are described. This should in future facilitate an assessment of the relevance of test methods for biological activities and responses of interest, of the quality of data produced, irrespective of whether these tests are based on manual protocols or assay protocols adapted for use on automated platforms or high-throughput screening systems (HTS).
Children can be more vulnerable than adults to chemicals. Considering global concern for children’s health, the OECD has been working to bring together knowledge and experiences to reduce risks to children’s health from chemicals.
The OECD has released Version 3.3 of the QSAR Toolbox. It contains many new features and functionality improvements, including the DART (Developmental and Reproductive Toxicity) model, among others. In addition, the QSAR Toolbox 3.3 contains updates of six databases (including ECHA CHEM), new QSAR models for explosive property and phototoxicity calculations, bug fixes and many other usability improvements.
English, PDF, 726kb
An IT system to develop and evaluate Adverse Outcome Pathways (AOP), the AOP Wiki, has been developed for testing by the Extended Advisory Group on Molecular Screening and Toxicogenomics and by AOP developers included in the work plan. The Wiki provides developers the necessary steps to capture scientific information in a user-friendly manner. The project is jointly led by the ECJRC and the USEPA.
This report includes the conclusions and recommendations of an expert workshop on the genotoxicity of nanomaterials, which was organized by OECD’s Working Party on Manufactured Nanomaterials. The main topic was the applicability of existing OECD Test Guidelines (TG) for chemical safety to nanomaterials.
OECD countries have developed PRTR system to track releases and transfers of potentially harmful chemicals. To improve PRTR system, OECD have analysed common elements (pollutants, sectors) in different PRTR systems, mainly focus on institutional arrangement. This serves as a common framework for different PRTR system, and supporting materials for a country that intends to develop or update its PRTR.
PRTR have been established throughout the world to track releases and transfers of potentially harmful chemicals. But most of the PRTR systems were designed without considering comparability, each PRTR has its own requirement of reporting chemicals and sectors. To harmonise globally, OECD reviewed the reporting chemicals and sectors across PRTR systems and produced proposal for harmonised lists of reporting pollutants.