The safety of Manufactured Nanomaterials is an important concern impacting regulatory bodies throughout the world. Due to their size, Manufactured Nanomaterials may require additional testing beyond the standard suite of tests used for other chemicals, to ensure that the impact on human health and the environment is fully understood - download Manufactured Nanomaterials Dossiers or search for Tested Endpoints.
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This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test.
The programme (or BioPesticides including microbials - bacteria, algae, protozoa viruses, fungi -, pheromones and semiochemicals, macrobials/invertebrates such as insects and nematodes, and plant extracts/botanicals) helps member countries to harmonise the methods and approaches used to assess biological pesticides.
A new publication is available in this series: Report on the Workshop on a Framework for the Development and use of Integrated Approaches to Testing and Assessment (No. 215).
Draft Guidance Document for Honeybees Larval Toxicity Test, Repeated Exposure; and Draft validation report – Results of the International ring test of the honeybee larval toxicity test, repeated exposure
The Toolbox is a software application intended to the use of governments, chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals.
Based on submissions provided by member countries, the analysis outlines experiences that can assist member countries in developing efficient and effective regulatory regimes. These include experiences regarding transitioning to a new chemical management regime and the (re)assessment of historical chemical approvals/notifications; and comparing policy objectives of different countries’ chemical management regimes.
An internet gateway providing direct free access to information on the properties of chemicals as well as to hazard and risk assessments. eChemPortal for access to health and environmental effects information prepared for government chemical review programs around the world. The new brochure is now available and highlights relevant information on the Portal.
The OECD eChemPortal, a web portal which offers comprehensive information on chemical substances, has been updated to offer better access to chemical classifications according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).
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This Test Guideline is designed for assessing the effects of chemicals on the reproductive output of the collembolans in soil. It is based on existing procedures (1) (2). The parthenogenetic Folsomia candida and sexually reproducing Folsomia fimetaria are two of the most accessible species of Collembola, and they are culturable and commercially available.