Latest Documents

The OECD QSAR Toolbox

The OECD has released Version 3.3 of the QSAR Toolbox. It contains many new features and functionality improvements, including the DART (Developmental and Reproductive Toxicity) model, and the general mechanistic Cramer schemes. In addition, the QSAR Toolbox 3.3 contains updates of six databases (including ECHA CHEM), new QSAR models for explosive property and phototoxicity calculations, bug fixes and many other usability improvements.

Series on Testing and Assessment: Performance Standards

Series on Testing and Assessment: Performance Standards

Expansion of Brazil's scope under OECD agreement on mutual acceptance of chemical safety data

In 2011, Brazil joined OECD’s Mutual Acceptance of Data (MAD) system ensuring that its chemical safety test data will be accepted by all 40 countries adhering to MAD. Originally limited to data developed in Brazil on pesticides, biocides and industrial chemicals, it now also includes veterinary products, feed additives, cosmetics, pharmaceutical products, sanitizers, wood preservative and treatments of effluents and natural ecosystems.

Good Laboratory Practice (GLP)

This is the OECD Good Laboratory Practice homepage. The primary objective of the OECD Principles of GLP is to ensure the generation of high quality and reliable test data related to the safety of industrial chemical substances.

A new guidance is now available to facilitate the ecological risk assessment of organometallic and organic metal salt substances

The OECD has published guidance to facilitate the ecological risk assessment of organometallic and organic metal salt substances. A strategy is presented based on key steps that first consider the fate of these substances in the environment, the identification of moieties of concern, and subsequently the selection of an appropriate path forward to either assess the inorganic moiety and/or the individual substance.

Launch of 2 OECD Test Guidelines on human hazard endpoint skin sensitisation

The OECD has just published two new Test Guidelines on human health hazard endpoint skin sensitisation. Skin sensitisation refers to an allergic response following skin contact with the tested chemical, as defined by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS).

OECD Substitution and Alternatives Assessment Toolbox

This toolbox is a compilation of resources relevant to chemical substitution and alternatives assessments. Alternative assessments are processes for identifying, comparing and selecting safer alternatives to replace hazardous chemicals with the objective of promoting sustainable production and consumption.

Biosafety and the Environmental Uses of Micro-Organisms

Micro-organisms play a fundamental role in the environment. Yet their role is the result of complex biogeochemical processes by consortia of micro-organisms and the function of individual species is not clear in many cases. This publication provides an overview of the current situation and relevant developments in environmental microbiology.

Biosafety and the Environmental Uses of Micro-Organisms - Conference Proceedings

Micro-organisms play a fundamental role in the environment. Yet their role is the result of complex biogeochemical processes by consortia of micro-organisms and the function of individual species is not clear in many cases.

This publication provides an overview of the current situation and relevant developments in environmental microbiology, as well as its potential application, which covers: use of micro-organisms for

Addendum Number 2 to the OECD Guiding Principles for Chemical Accident Prevention, Preparedness and Response (2nd ed.) to Address Natural Hazards Triggering Technological Accidents (Natechs)

An addendum to the OECD Guiding Principles on Chemical Accident Prevention, Preparedness and Response to address Natural Hazards Triggering Technological Accidents (Natech) Risk Management has just been published. The addendum consists of a number of amendments to the Guiding Principles and the addition of a new Chapter to provide more detailed guidance on Natech prevention, preparedness and response.