In a reverse gene mutation assay in bacteria (MRID if avalable), strains [specify] of S. typhimurium [or other acceptable bacterial strains, ie., E. coli]  were exposed to [Chemical name, (% a.i.), include solvent if appropriate] at concentrations of , , ,  Fg/plate in the presence and absence of mammalian metabolic activation [specify if plate co-incubation or pre-incubation]

 

(Chemical name) was tested [up to cytotoxic (or insoluble) concentrations or limit concentration (5000 Fg/plate or 5 FL/plate), include other details as appropriate](quantitate if positive for number of revertants e.g., a dose related increase to 782 revertants at the highest concentration vs. 110 revertants in control for strain TA 100).  The positive controls induced (did not induce) the appropriate responses in the corresponding strains.   There was (no) evidence (or a concentration related positive response) of induced mutant colonies over background.

 

This study is classified as [acceptable or unacceptable(why)].  This study satisfies (does not satisfy)  the requirement for Test Guideline  OPPTS 870.51001; OECD 471 for in vitro mutagenicity (bacterial reverse gene mutation) data. [If it does not satisfy the requirement, concisely list only major deficiencies or refer to deficiency section.]