In a  repeat-dose dermal toxicity study (MRID  if available),  [Chemical name (%a.i.)] was applied to the shaved skin of [(# of animals) species, strain]/sex/dose at dose levels of 0, x, x, x  mg/kg bw/day, 6 hours/day for 5 days/week during a 90-day period.

 

[Describe toxicity briefly.  If there is no toxicity, state that there were no compound related effects in mortality, clinical signs, body weight, food consumption, hematology, clinical chemistry, organ weights, or gross and histologic pathology.  Note if there was a LOAEL/NOAEL for clinical findings (for Acute reference dose consideration during subsequent risk assessment)]The LOAEL is      , based on           .  The NOAEL is    .

 

This dermal toxicity study in the (species) is [acceptable, unacceptable(why); note if it is a range-finding study] and satisfies (does not satisfy) the guideline requirement for a repeat-dose dermal toxicity study (OPPTS 870.3250  [species]) ; OECD 410 in [species].  [If it does not satisfy the requirement, concisely list only major deficiencies or refer to deficiency section.]