In a chronic toxicity study (MRID  if available) Chemical name, (% a.i.)  was administered to [(# of animals) species, strain]/sex/dose in [diet, water, by capsule, by gavage] at dose levels of (dose levels) ppm (0, , ,    mg/kg bw/day) for (duration).

 

[Describe toxicity briefly.  If no toxicity state that there were no compound related effects in mortality, clinical signs, body weight, food consumption, hematology, clinical chemistry, urinalysis, organ weights, or gross and histologic (including tumours) pathology]The NOAEL is  . The LOAEL is      , based on           .

 

This chronic study in the (species) is [acceptable, unacceptable (why)] and satisfies (does not satisfy) the guideline requirement for a chronic oral study (OPPTS 870.4100), OECD 452 in [species]. [If it does not satisfy the requirement, concisely list only major deficiencies or refer to deficiency section.]