Table #: Natural Killer Cell Assay
|
Test Group (n = #) |
Effector:Target Ratio (b) eg., |
LU/107 cells (c) (Specific activity) |
LU/spleen (c) (Total activity) | |||||
|
6.25:1 |
12.5:1 |
25:1 |
50:1 |
100:1 |
200:1 | |||
|
Male | ||||||||
|
Control |
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Dose 1 |
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Dose 2 |
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Dose 3 |
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|
|
|
|
Positive Control (name of substance) |
|
|
|
|
|
|
|
|
|
Female | ||||||||
|
Control |
|
|
|
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|
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|
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|
Dose 1 |
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|
|
|
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Dose 2 |
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|
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|
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Dose 3 |
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|
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|
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|
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Positive Control (name of substance) |
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b Values are expressed as percent cytotoxicity
c Values expressed as lytic unit (LU) were LU is defined as the number of splenocytes required to kill 10% of the target cells
Effector cells: NK cells. Target cells: YAC-1 lymphoma cells
* Significantly different (p <0.05) from the control.
** Significantly different (p <0.01) from the control.