Table #: Study design – Animal assignment

 

                                  Dose Group ppm (mg/kg/day)

Experimental Parameter

control

dose 1

dose 2

dose 3

Total number of Animals/sex/group

 

 

 

 

Behavioral Testing (FOB, Motor Activity)

10/sex

10/sex

10/sex

10/sex

Neuropathology

  6/sex

  6/sex

  6/sex

  6/sex

Blood  cholinesterase determination

  5/sex

  5/sex

  5/sex

  5/sex

Brain cholinesterase determination

 5/sex

  5/sex

  5/sex

  5/sex